Publications
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| Journal: Mol. Cell. Biol. | Jan-12 |
| O2 Regulates Skeletal Muscle Progenitor Differentiation through Phosphatidylinositol 3-Kinase/AKT Signaling |
| Journal: J Nat Cancer Inst | Dec-11 |
| Differentiation Therapy: Targeting Human Renal Cancer Stem Cells with Interleukin 15 |
| Journal: J. Biol. Chem. | Dec-11 |
| Endogenous Myoglobin in Breast Cancer Is Hypoxia-inducible by Alternative Transcription and Functions to Impair Mitochondrial Activity: A ROLE IN TUMOR SUPPRESSION? |
| Journal: Cancer Res | Dec-11 |
| Phosphorylation of Carbonic Anhydrase IX Controls Its Ability to Mediate Extracellular Acidification in Hypoxic Tumors |
| Journal: Mol. Cancer Ther. | Dec-11 |
| The Novel Bcl-2 Inhibitor ABT-737 Is More Effective in Hypoxia and Is Able to Reverse Hypoxia-Induced Drug Resistance in Neuroblastoma Cells |
| Journal: J. Virol. | Dec-11 |
| Hypoxia Induces the Gene Expression and Extracellular Transmission of Persistent Lymphocytic Choriomeningitis Virus |
| Journal: J. Biol. Chem. | Dec-11 |
| Inhibition of Glycolytic Enzymes Mediated by Pharmacologically Activated p53: TARGETING WARBURG EFFECT TO FIGHT CANCER |
| Journal: Genes and Development | Dec-11 |
| The role of nuclear lamin B1 in cell proliferation and senescence |
| Journal: Rheumatology | Nov-11 |
| Hypoxia differentially affects IL-1β-stimulated MMP-1 and MMP-13 expression of fibroblast-like synoviocytes in an HIF-1α-dependent manner |
| Journal: Nucleic Acids Res | Nov-11 |
| Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling |
| Journal: J. Biol. Chem. | Nov-11 |
| Dihydroceramide-based Response to Hypoxia |
| Journal: Mol. Biol.Cell | Nov-11 |
| The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH |
| Journal: J. Med, Microbiol. | Nov-11 |
| Differentiation of division I (cfiA-negative) and division II (cfiA-positive) Bacteroides fragilis strains by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry |
| Journal: J. Immunol | Nov-11 |
| IL-1α and IL-1β Recruit Different Myeloid Cells and Promote Different Stages of Sterile Inflammation |
| Journal: J.Immunol | Oct-11 |
| Hypoxia-Dependent Inhibition of Tumor Cell Susceptibility to CTL-Mediated Lysis Involves NANOG Induction in Target Cells |
| Journal: PNAS | Oct-11 |
| CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors |
| Journal: Genetics | Oct-11 |
| Genetic Analysis of Desiccation Tolerance in Saccharomyces cerevisiae |
| Journal: PNAS | Sep-11 |
| Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells |
| Journal: Cancer Res | Sep-11 |
| Blocking Hypoxia-Induced Autophagy in Tumors Restores Cytotoxic T-Cell Activity and Promotes Regression |
| Journal: J. Biol. Chem. | Sep-11 |
| Quantitative Mass Spectrometry Reveals Dynamics of Factor-inhibiting Hypoxia-inducible Factor-catalyzed Hydroxylation |
| Journal: J. Leukoc. Biol. | Sep-11 |
| Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1α (HIF1A) and result in differential HIF1A-dependent gene expression |
| Journal: Mol. Cell. Biol. | Sep-11 |
| Hypoxia Leads to Na,K-ATPase Downregulation via Ca2+ Release-Activated Ca2+ Channels and AMPK Activation |
| Journal: PNAS | Aug-11 |
| Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2–mediated heparin-binding EGF signaling in endothelial cells |
| Journal: Cancer Res | Aug-11 |
| Overcoming Hypoxia-Induced Apoptotic Resistance through Combinatorial Inhibition of GSK-3β and CDK1 |
| Journal: Mol. Cancer Res. | Jun-11 |
| Differential Hypoxic Regulation of Hypoxia-Inducible Factors 1α and 2α |
| Journal: Cancer Res | Jun-11 |
| Glycolytic Phenotype and AMP Kinase Modify the Pathologic Response of Tumor Xenografts to VEGF Neutralization |
| Journal: Infect. Immun. | Jun-11 |
| Fusobacterium nucleatum Infection of Colonic Cells Stimulates MUC2 Mucin and Tumor Necrosis Factor Alpha |
| Journal: Cancer Res | Jun-11 |
| The Hypoxia-Associated Factor Switches Cells from HIF-1α- to HIF-2α-Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion |
| Journal: Am J Heart Circ Physiol | May-11 |
| Interventricular heterogeneity in rat heart responses to hypoxia: the tuning of glucose metabolism, ion gradients, and function |
| Journal: Invest.Opthamology Vis. Sci. | Apr-11 |
| Hypoxia Increases Glutamate Secretion by Retinal Pigmented Epithelial Cells |
| Journal: J. Biol. Chem. | Apr-11 |
| Cellular Hypoxia of Pancreatic β-Cells Due to High Levels of Oxygen Consumption for Insulin Secretion in Vitro |
| Journal: Infect. Immun. | Apr-11 |
| Lipoxin A4 Inhibits Porphyromonas gingivalis-Induced Aggregation and Reactive Oxygen Species Production by Modulating Neutrophil-Platelet Interaction and CD11b Expression |
| Journal: Am J Physiol Lung Cell Mol Physiol | Apr-11 |
| Hypoxia increases transepithelial electrical conductance and reduces occludin at the plasma membrane in alveolar epithelial cells via PKC- and PP2A pathway |
| Journal: Eukaryot Cell | Apr-11 |
| Sch9 Kinase Integrates Hypoxia and CO2 Sensing To Suppress Hyphal Morphogenesis in Candida albicans |
| Journal: Cancer Res | Mar-11 |
| The HIF-1–Inducible Lysyl Oxidase Activates HIF-1 via the Akt Pathway in a Positive Regulation Loop and Synergizes with HIF-1 in Promoting Tumor Cell Growth |
| Journal: J Endocrinol | Feb-11 |
| Superoxide induced by a high-glucose concentration attenuates production of angiogenic growth factors in hypoxic mouse mesenchymal stem cells |
| Journal: Haematologica | Feb-11 |
| Glucose availability in hypoxia regulates the selection of chronic myeloid leukemia progenitor subsets with different resistance to imatinib-mesylate |
| Journal: J Immunol | Jan-11 |
| Hypoxia Selectively Inhibits Respiratory Burst Activity and Killing of Staphylococcus aureus in Human Neutrophils |
| Journal: Dental Research | Jan-11 |
| Prevotella intermedia Induces Prostaglandin E2 via Multiple Signaling Pathways |
| Journal: Cancer Res | Dec-10 |
| Combinatorial Regulation of Neuroblastoma Tumor Progression by N-Myc and Hypoxia Inducible Factor HIF-1 |
| Journal: Am J Phyisol Reg Int Comp Physiol | Dec-10 |
| ID family protein expression and regulation in hypoxic pulmonary hypertension |
| Journal: Am J Phyisol Reg Int Comp Physiol | Dec-10 |
| Late-gestational systemic hypoxia leads to a similar early gene response in mouse placenta and developing brain |
| Journal: Cancer Res | Dec-10 |
| Downregulation of c-MYC Protein Levels Contributes to Cancer Cell Survival under Dual Deficiency of Oxygen and Glucose |
| Journal: Am J Phyisol Reg Int Comp Physiol | Dec-10 |
| Impaired ventilatory acclimatization to hypoxia in female mice overexpressing erythropoietin: unexpected deleterious effect of estradiol in carotid bodies |
| Journal: Eukaryot Cell | Nov-10 |
| Regulation of the Hypoxic Response in Candida albicans |
| Journal: Mol Cell Biol | Oct-10 |
| Renal Oxygenation Suppresses VHL Loss-Induced Senescence That Is Caused by Increased Sensitivity to Oxidative Stress |
| Journal: Mol Cell Biol | Oct-10 |
| Mechanism of Hypoxia-Induced NFkB |
| Journal: Cancer Res | Oct-10 |
| Contextual Synthetic Lethality of Cancer Cell Kill Based on the Tumor Microenvironment |
| Journal: Mol Cell Biol | Sep-10 |
| Hypoxia-inducible Factor-1 Activation in Nonhypoxic Conditions: The Essential Role of Mitochondrial-derived Reactive Oxygen Species |
| Journal: J Cell Sci | Sep-10 |
| Casein kinase 1 regulates human hypoxia-inducible factor HIF-1 |
| Journal: Am J Pathol | Sep-10 |
| A Combination of Hypoxia and Lipopolysaccharide Activates Tristetraprolin to Destabilize Proinflammatory mRNAs such as Tumor Necrosis Factor- |
| Journal: J Immunol | Sep-10 |
| Distinct Cell Death Programs in Monocytes Regulate Innate Responses Following Challenge with Common Causes of Invasive Bacterial Disease |
| Journal: Cancer Res | Sep-10 |
| Aminoflavone, a Ligand of the Aryl Hydrocarbon Receptor, Inhibits HIF-1 Expression in an AhR-Independent Fashion |
| Journal: PNAS | Aug-10 |
| From the Cover: Inaugural Article: Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development |
| Journal: J Biol Chem | Aug-10 |
| Toxoplasma gondii Activates Hypoxia-inducible Factor (HIF) by Stabilizing the HIF-1 Subunit via Type I Activin-like Receptor Kinase Receptor Signaling |
| Journal: PNAS | Aug-10 |
| HIF-2 deletion promotes Kras-driven lung tumor development |
| Journal: Cancer Res | Aug-10 |
| Transplanting Normal Vascular Proangiogenic Cells to Tumor-Bearing Mice Triggers Vascular Remodeling and Reduces Hypoxia in Tumors |
| Journal: J Immunol | Aug-10 |
| Acute Hypoxia Induces HIF-Independent Monocyte Adhesion to Endothelial Cells through Increased Intercellular Adhesion Molecule-1 Expression: The Role of Hypoxic Inhibition of Prolyl Hydroxylase Activity for the Induction of NF-B |
| Journal: Cancer Res | Jul-10 |
| Hypoxic Conversion of SMAD7 Function from an Inhibitor into a Promoter of Cell Invasion |
| Journal: ASCO Meeting Abstracts | May-10 |
| Effect of lenalidomide on hypoxia-induced HIF-1 signaling and the invasive phenotype in epithelial solid tumor cells. |
| Journal: Int J Sys Evol Biol | May-10 |
| Anaerostipes butyraticus sp. nov., an anaerobic, butyrate-producing bacterium from Clostridium cluster XIVa isolated from broiler chicken caecal content, and emended description of the genus Anaerostipes |
| Journal: Blood | May-10 |
| Absence of functional EpoR expression in human tumor cell lines |
| Journal: Brain | Apr-10 |
| A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 |
| Journal: J Physio | Apr-10 |
| Effects of substitution of Cx43 by Cx32 on myocardial energy metabolism, tolerance to ischaemia and preconditioning protection |
| Journal: Carcinognenesis | Mar-10 |
| Hypoxia activates the cyclooxygenase-2–prostaglandin E synthase axis |
| Journal: Proceedings of the National Academy of Sciences | Feb-10 |
| Differential release of chromatin-bound IL-1 discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation Idan Cohen, Peleg Rider, Yaron Carmi, Alex Braiman, Shahar Dotan, Malka R. White, Elena Voronov, Michael U. Martin, Charles A. Dinarello, and Ron N. Apte PNAS, Feb 2010; 107: 2574 - 2579. |
| Journal: Journal of Biological Chemistry | Feb-10 |
| Hypoxia-activated Smad3-specific Dephosphorylation by PP2A Pekka T. Heikkinen, Marika Nummela, Suvi-Katri Leivonen, Jukka Westermarck, Caroline S. Hill, Veli-Matti Kähäri, and Panu M. Jaakkola J. Biol. Chem., Feb 2010; 285: 3740 - 3749. |
| Journal: Journal of Leukocyte Biology | Feb-10 |
| Induction of HIF-1 and the glycolytic pathway alters apoptotic and differentiation profiles of activated human T cells Anis Larbi, Henning Zelba, David Goldeck, and Graham Pawelec J. Leukoc. Biol., Feb 2010; 87: 265 - 273. |
| Journal: American Journal of Pathology | Feb-10 |
| Human Nephrosclerosis Triggers a Hypoxia-Related Glomerulopathy Matthias A. Neusser, Maja T. Lindenmeyer, Anton G. Moll, Stephan Segerer, Ilka Edenhofer, Kontheari Sen, Daniel P. Stiehl, Matthias Kretzler, Hermann-Josef Gröne, Detlef Schlöndorff, and Clemens D. Cohen Am. J. Pathol., Feb 2010; 176: 594 - 607. |
| Journal: Cancer Research | Feb-10 |
| Effects of Acute versus Chronic Hypoxia on DNA Damage Responses and Genomic Instability Isabel M. Pires, Zuzana Bencokova, Manuela Milani, Lisa K. Folkes, Ji-Liang Li, Mike R. Stratford, Adrian L. Harris, and Ester M. Hammond Cancer Res., Feb 2010; 70: 925 - 935. |
| Journal: Journal of Biological Chemistry | Jan-10 |
| FM19G11, a New Hypoxia-inducible Factor (HIF) Modulator, Affects Stem Cell Differentiation Status Victoria Moreno-Manzano, Francisco J. Rodríguez-Jiménez, Jose L. Aceña-Bonilla, Santos Fustero-Lardíes, Slaven Erceg, Joaquin Dopazo, David Montaner, Miodrag Stojkovic, and Jose M. Sánchez-Puelles J. Biol. Chem., Jan 2010; 285: 1333 - 1342. |
| Journal: Journal of Biological Chemistry | Jan-10 |
| FM19G11, a New Hypoxia-inducible Factor (HIF) Modulator, Affects Stem Cell Differentiation Status Victoria Moreno-Manzano, Francisco J. Rodríguez-Jiménez, Jose L. Aceña-Bonilla, Santos Fustero-Lardíes, Slaven Erceg, Joaquin Dopazo, David Montaner, Miodrag Stojkovic, and Jose M. Sánchez-Puelles J. Biol. Chem., Jan 2010; 285: 1333 - 1342. |
| Journal: Cancer Research | Jan-10 |
| Prolyl Hydroxylases 2 and 3 Act in Gliomas as Protective Negative Feedback Regulators of Hypoxia-Inducible Factors Anne-Theres Henze, Johanna Riedel, Tanja Diem, Julia Wenner, Ingo Flamme, Jacques Pouyseggur, Karl H. Plate, and Till Acker Cancer Res., Jan 2010; 70: 357 - 366. |
| Journal: Molecular and Cellular Biology | Jan-10 |
| Regulation of the Histone Demethylase JMJD1A by Hypoxia-Inducible Factor 1 Enhances Hypoxic Gene Expression and Tumor Growth Adam J. Krieg, Erinn B. Rankin, Denise Chan, Olga Razorenova, Sully Fernandez, and Amato J. Giaccia Mol. Cell. Biol., Jan 2010; 30: 344 - 353. |
| Journal: Cancer Research | Dec-09 |
| Hypoxia-Regulated Delta-like 1 Homologue Enhances Cancer Cell Stemness and Tumorigenicity Yuri Kim, Qun Lin, Daniel Zelterman, and Zhong Yun Cancer Res., Dec 2009; 69: 9271 - 9280. |
| Journal: American Journal of Physiology - Lung Cellular and Molecular Physiology | Dec-09 |
| Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxia-inducible factor 1 Guofei Zhou, Laura A. Dada, Minghua Wu, Aileen Kelly, Humberto Trejo, Qiyuan Zhou, John Varga, and Jacob I. Sznajder Am J Physiol Lung Cell Mol Physiol, Dec 2009; 297: L1120 - L1130. |
| Journal: Cancer Research | Dec-09 |
| Hypoxia Regulates Insulin Receptor Substrate-2 Expression to Promote Breast Carcinoma Cell Survival and Invasion Katerina Mardilovich and Leslie M. Shaw Cancer Res., Dec 2009; 69: 8894 - 8901. |
| Journal: Journal of Biological Chemistry | Dec-09 |
| An Integrated Approach for Experimental Target Identification of Hypoxia-induced miR-210 Pasquale Fasanaro, Simona Greco, Maria Lorenzi, Mario Pescatori, Maura Brioschi, Ritu Kulshreshtha, Cristina Banfi, Andrew Stubbs, George A. Calin, Mircea Ivan, Maurizio C. Capogrossi, and Fabio Martelli J. Biol. Chem., Dec 2009; 284: 35134 - 35143. |
| Journal: FASEB Journal | Nov-09 |
| Mitochondrial reactive oxygen species are required for hypoxia-induced degradation of keratin intermediate filaments Ni Na, Navdeep S. Chandel, Juan Litvan, and Karen M. Ridge FASEB J, Nov 2009; 10.1096/fj.08-128967. |
| Journal: Eukaryotic Cell | Nov-09 |
| Conservation of the Sterol Regulatory Element-Binding Protein Pathway and Its Pathobiological Importance in Cryptococcus neoformans Yun C. Chang, Susham S. Ingavale, Clara Bien, Peter Espenshade, and Kyung J. Kwon-Chung Eukaryot. Cell, Nov 2009; 8: 1770 - 1779. |
| Journal: Proceedings of the National Academy of Sciences | Oct-09 |
| IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction Meijing Wang, Jiangning Tan, Yue Wang, Kirstan K. Meldrum, Charles A. Dinarello, and Daniel R. Meldrum PNAS, Oct 2009; 106: 17499 - 17504. |
| Journal: The Journal of Immunology | Oct-09 |
| The Role of Macrophage-Derived IL-1 in Induction and Maintenance of Angiogenesis Yaron Carmi, Elena Voronov, Shahar Dotan, Nitza Lahat, Michal A. Rahat, Mina Fogel, Monika Huszar, Malka R. White, Charles A. Dinarello, and Ron N. Apte J. Immunol., Oct 2009; 183: 4705 - 4714. |
| Journal: Clinical Cancer Research | Oct-09 |
| Identification of a Novel Small Molecule HIF-1 Translation Inhibitor Takuhito Narita, Shaoman Yin, Christine F. Gelin, Carlos S. Moreno, Manuel Yepes, K.C. Nicolaou, and Erwin G. Van Meir Clin. Cancer Res., Oct 2009; 15: 6128 - 6136. |
| Journal: Toxicology and Industrial Health | Sep-09 |
| Arsenic trioxide inhibits the growth of human lung cancer cell lines via cell cycle arrest and induction of apoptosis at both normoxia and hypoxia Qu Ge-ping, Xiu Qing-Yu, Li Bing, Liu Yong-an, and Zhang Ling-Zhen Toxicology and Industrial Health, Sep 2009; 25: 505 - 515. |
| Journal: Proceedings of the National Academy of Sciences | Sep-09 |
| HIF-2 maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells Alexander Pietras, Loen M. Hansford, A. Sofie Johnsson, Esther Bridges, Jonas Sjölund, David Gisselsson, Matilda Rehn, Siv Beckman, Rosa Noguera, Samuel Navarro, Jörg Cammenga, Erik Fredlund, David R. Kaplan, and Sven Påhlman PNAS, Sep 2009; 106: 16805 - 16810. |
| Journal: Blood | Sep-09 |
| The supernatant of apoptotic cells causes transcriptional activation of hypoxia-inducible factor–1 in macrophages via sphingosine-1-phosphate and transforming growth factor- Barbara Herr, Jie Zhou, Christian Werno, Heidi Menrad, Dmitry Namgaladze, Andreas Weigert, Nathalie Dehne, and Bernhard Brüne Blood, Sep 2009; 114: 2140 - 2148. |
| Journal: Cancer Research | Aug-09 |
| Tumor Vascular Changes Mediated by Inhibition of Oncogenic Signaling Naseer Qayum, Ruth J. Muschel, Jae Hong Im, Lukxmi Balathasan, Cameron J. Koch, Sonal Patel, W. Gillies McKenna, and Eric J. Bernhard Cancer Res., Aug 2009; 69: 6347 - 6354. |
| Journal: Journal of Biological Chemistry | Aug-09 |
| Activation of Cu,Zn-Superoxide Dismutase in the Absence of Oxygen and the Copper Chaperone CCS Jeffry M. Leitch, Laran T. Jensen, Samantha D. Bouldin, Caryn E. Outten, P. John Hart, and Valeria C. Culotta J. Biol. Chem., Aug 2009; 284: 21863 - 21871. |
| Journal: Proceedings of the National Academy of Sciences | Aug-09 |
| Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events Steffi Lehmann, Daniel P. Stiehl, Michael Honer, Marco Dominietto, Ruth Keist, Ivana Kotevic, Kristin Wollenick, Simon Ametamey, Roland H. Wenger, and Markus Rudin PNAS, Aug 2009; 106: 14004 - 14009. |
| Journal: Proceedings of the National Academy of Sciences | Aug-09 |
| HIF2 inhibition promotes p53 pathway activity, tumor cell death, and radiation responses Jessica A. Bertout, Amar J. Majmundar, John D. Gordan, Jennifer C. Lam, Dara Ditsworth, Brian Keith, Eric J. Brown, Katherine L. Nathanson, and M. Celeste Simon PNAS, Aug 2009; 106: 14391 - 14396. |
| Journal: American Journal of Pathology | Jul-09 |
| Expression and Functional Regulation of Myoglobin in Epithelial Cancers Simona Emilia Flonta, Sabrina Arena, Alberto Pisacane, Paolo Michieli, and Alberto Bardelli Am. J. Pathol., Jul 2009; 175: 201 - 206. |
| Journal: FASEB Journal | Jul-09 |
| Proapoptotic Noxa is required for particulate matter-induced cell death and lung inflammation Daniela Urich, Saul Soberanes, Zach Burgess, Sergio E. Chiarella, Andrew J. Ghio, Karen M. Ridge, David W. Kamp, Navdeep S. Chandel, Gökhan M. Mutlu, and G. R. Scott Budinger FASEB J, Jul 2009; 23: 2055 - 2064. |
| Journal: Journal of Biological Chemistry | Jul-09 |
| Degradation of Sterol Regulatory Element-binding Protein Precursor Requires the Endoplasmic Reticulum-associated Degradation Components Ubc7 and Hrd1 in Fission Yeast Bridget T. Hughes, Christine C. Nwosu, and Peter J. Espenshade J. Biol. Chem., Jul 2009; 284: 20512 - 20521. |
| Journal: Molecular Cancer Research | Jul-09 |
| Vascular Caveolin Deficiency Supports the Angiogenic Effects of Nitrite, a Major End Product of Nitric Oxide Metabolism in Tumors Françoise Frérart, Irina Lobysheva, Bernard Gallez, Chantal Dessy, and Olivier Feron Mol. Cancer Res., Jul 2009; 7: 1056 - 1063. |
| Journal: Molecular Cancer Therapeutics | Jul-09 |
| Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition Annamaria Rapisarda, Melinda Hollingshead, Badarch Uranchimeg, Carrie A. Bonomi, Suzanne D. Borgel, John P. Carter, Bradley Gehrs, Mark Raffeld, Robert J. Kinders, Ralph Parchment, Miriam R. Anver, Robert H. Shoemaker, and Giovanni Melillo Mol. Cancer Ther., Jul 2009; 8: 1867 - 1877. |
| Journal: Molecular and Cellular Biology | Jul-09 |
| 1-AMP-Activated Protein Kinase Regulates Hypoxia-Induced Na,K-ATPase Endocytosis via Direct Phosphorylation of Protein Kinase C Galina A. Gusarova, Laura A. Dada, Aileen M. Kelly, Chaya Brodie, Lee A. Witters, Navdeep S. Chandel, and Jacob I. Sznajder Mol. Cell. Biol., Jul 2009; 29: 3455 - 3464. |
| Journal: Blood | Jun-09 |
| The supernatant of apoptotic cells causes transcriptional activation of HIF-1 in macrophages via sphingosine-1-phosphate and transforming growth factor- Barbara Herr, Jie Zhou, Christian Werno, Heidi Menrad, Dmitry Namgaladze, Andreas Weigert, Nathalie Dehne, and Bernhard Brüne Blood, Jun 2009; 10.1182/blood-2009-01-201889. |
| Journal: Applied and Environmental Microbiology | Jun-09 |
| Hypoxic Adaptation by Efg1 Regulates Biofilm Formation by Candida albicans Catrin Stichternoth and Joachim F. Ernst Appl. Envir. Microbiol., Jun 2009; 75: 3663 - 3672. |
| Journal: American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | Jun-09 |
| High glucose concentration in cell culture medium does not acutely affect human mesenchymal stem cell growth factor production or proliferation Brent R. Weil, Aaron M. Abarbanell, Jeremy L. Herrmann, Yue Wang, and Daniel R. Meldrum Am J Physiol Regulatory Integrative Comp Physiol, Jun 2009; 296: R1735 - R1743. |
| Journal: Arteriosclerosis, Thrombosis, and Vascular Biology | Jun-09 |
| Sphingosine-1-Phosphate: A Novel Nonhypoxic Activator of Hypoxia-Inducible Factor-1 in Vascular Cells Maude D. Michaud, Geneviève A. Robitaille, Jean-Philippe Gratton, and Darren E. Richard Arterioscler. Thromb. Vasc. Biol., Jun 2009; 29: 902 - 908. |
| Journal: The Journal of Nuclear Medicine | Jun-09 |
| Imaging of HIF-1-Active Tumor Hypoxia Using a Protein Effectively Delivered to and Specifically Stabilized in HIF-1-Active Tumor Cells Takashi Kudo, Masashi Ueda, Yuji Kuge, Takahiro Mukai, Shotaro Tanaka, Maki Masutani, Yasushi Kiyono, Shinae Kizaka-Kondoh, Masahiro Hiraoka, and Hideo Saji J. Nucl. Med., Jun 2009; 50: 942 - 949. |
| Journal: Applied and Environmental Microbiology | May-09 |
| Stereospecific Biotransformation of Dihydrodaidzein into (3S)-Equol by the Human Intestinal Bacterium Eggerthella Strain Julong 732 Mihyang Kim, Su-Il Kim, Jaehong Han, Xiu-Ling Wang, Dae-Geun Song, and Soo-Un Kim Appl. Envir. Microbiol., May 2009; 75: 3062 - 3068. |
| Journal: Molecular and Cellular Biology | May-09 |
| Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains Grégory Bellot, Raquel Garcia-Medina, Pierre Gounon, Johanna Chiche, Danièle Roux, Jacques Pouysségur, and Nathalie M. Mazure Mol. Cell. Biol., May 2009; 29: 2570 - 2581. |
| Journal: Clinical Cancer Research | May-09 |
| Loss of VHL and Hypoxia Provokes PAX2 Up-Regulation in Clear Cell Renal Cell Carcinoma Van-Duc Luu, Gunther Boysen, Kirsten Struckmann, Silvia Casagrande, Adriana von Teichman, Peter J. Wild, Tullio Sulser, Peter Schraml, and Holger Moch Clin. Cancer Res., May 2009; 15: 3297 - 3304. |
| Journal: Molecular and Cellular Biology | Apr-09 |
| Key Role for Activin B in Cellular Transformation after Loss of the von Hippel-Lindau Tumor Suppressor Ingrid Wacker, Martin Sachs, Karl Knaup, Michael Wiesener, Jörg Weiske, Otmar Huber, Ziya Akçetin, and Jürgen Behrens Mol. Cell. Biol., Apr 2009; 29: 1707 - 1718. |
| Journal: Cancer Research | Apr-09 |
| v3/v5 Integrins-FAK-RhoB: A Novel Pathway for Hypoxia Regulation in Glioblastoma Nicolas Skuli, Sylvie Monferran, Caroline Delmas, Gilles Favre, Jacques Bonnet, Christine Toulas, and Elizabeth Cohen-Jonathan Moyal Cancer Res., Apr 2009; 69: 3308 - 3316. |
| Journal: Molecular Cancer Therapeutics | Apr-09 |
| The selective hypoxia inducible factor-1 inhibitor PX-478 provides in vivo radiosensitization through tumor stromal effects David L. Schwartz, Garth Powis, Arun Thitai-Kumar, Yi He, James Bankson, Ryan Williams, Robert Lemos, Junghwan Oh, Andrei Volgin, Suren Soghomonyan, Ryuichi Nishii, Mian Alauddin, Uday Mukhopadhay, Zhenghong Peng, William Bornmann, and Juri Gelovani Mol. Cancer Ther., Apr 2009; 8: 947 - 958. |
| Journal: Journal of Biological Chemistry | Apr-09 |
| Erythrocytosis-associated HIF-2 Mutations Demonstrate a Critical Role for Residues C-terminal to the Hydroxylacceptor Proline Paul W. Furlow, Melanie J. Percy, Scott Sutherland, Charlene Bierl, Mary Frances McMullin, Stephen R. Master, Terence R. J. Lappin, and Frank S. Lee J. Biol. Chem., Apr 2009; 284: 9050 - 9058. |
| Journal: Molecular Cancer Research | Mar-09 |
| Hypoxia Enhances Sphingosine Kinase 2 Activity and Provokes Sphingosine-1-Phosphate-Mediated Chemoresistance in A549 Lung Cancer Cells Steffen E. Schnitzer, Andreas Weigert, Jie Zhou, and Bernhard Brüne Mol. Cancer Res., Mar 2009; 7: 393 - 401. |
| Journal: The Journal of Immunology | Mar-09 |
| The Cooperative Induction of Hypoxia-Inducible Factor-1 and STAT3 during Hypoxia Induced an Impairment of Tumor Susceptibility to CTL-Mediated Cell Lysis Muhammad Zaeem Noman, Stéphanie Buart, Jos Van Pelt, Catherine Richon, Meriem Hasmim, Nathalie Leleu, Wictoria Maria Suchorska, Abdelali Jalil, Yann Lecluse, Faten El Hage, Massimo Giuliani, Christophe Pichon, Bruno Azzarone, Nathalie Mazure, Pedro Romero, Fathia Mami-Chouaib, and Salem Chouaib J. Immunol., Mar 2009; 182: 3510 - 3521. |
| Journal: The Journal of Physiology | Mar-09 |
| Effect of intracellular lipid droplets on cytosolic Ca2+ and cell death during ischaemia–reperfusion injury in cardiomyocytes Ignasi Barba, Laia Chavarria, Marisol Ruiz-Meana, Maribel Mirabet, Esperanza Agulló, and David Garcia-Dorado J. Physiol., Mar 2009; 587: 1331 - 1341. |
| Journal: The Journal of Immunology | Mar-09 |
| Macrophage Oxygen Sensing Modulates Antigen Presentation and Phagocytic Functions Involving IFN- Production through the HIF-1 Transcription Factor Bárbara Acosta-Iborra, Ainara Elorza, Isabel M. Olazabal, Noa B. Martín-Cofreces, Silvia Martin-Puig, Marta Miró, María J. Calzada, Julián Aragonés, Francisco Sánchez-Madrid, and Manuel O. Landázuri J. Immunol., Mar 2009; 182: 3155 - 3164. |
| Journal: Blood | Feb-09 |
| CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure Michael Fiegl, Ismael Samudio, Karen Clise-Dwyer, Jared K. Burks, Zakar Mnjoyan, and Michael Andreeff Blood, Feb 2009; 113: 1504 - 1512. |
| Journal: Cancer Research | Feb-09 |
| The Role of Tumor Cell–Derived Connective Tissue Growth Factor (CTGF/CCN2) in Pancreatic Tumor Growth Kevin L. Bennewith, Xin Huang, Christine M. Ham, Edward E. Graves, Janine T. Erler, Neeraja Kambham, Jonathan Feazell, George P. Yang, Albert Koong, and Amato J. Giaccia Cancer Res., Feb 2009; 69: 775 - 784. |
| Journal: Journal of Biological Chemistry | Feb-09 |
| SWI/SNF Regulates the Cellular Response to Hypoxia Niall S. Kenneth, Sharon Mudie, Patrick van Uden, and Sonia Rocha J. Biol. Chem., Feb 2009; 284: 4123 - 4131. |
| Journal: Cancer Research | Feb-09 |
| The Hypoxia-Activated ProDrug AQ4N Penetrates Deeply in Tumor Tissues and Complements the Limited Distribution of Mitoxantrone Olivier Trédan, Alaina B. Garbens, Alshad S. Lalani, and Ian F. Tannock Cancer Res., Feb 2009; 69: 940 - 947. |
| Journal: Clinical Cancer Research | Jan-09 |
| Reoxygenation of Hypoxic Glioblastoma Multiforme Cells Potentiates the Killing Effect of an Interleukin-13-Based Cytotoxin Tie Fu Liu, Jiaozhong Cai, Denise M. Gibo, and Waldemar Debinski Clin. Cancer Res., Jan 2009; 15: 160 - 168. |
| Journal: Molecular Cancer Therapeutics | Jan-09 |
| Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells Helen M. Pettersson, Alexander Pietras, Matilda Munksgaard Persson, Jenny Karlsson, Leif Johansson, Maria C. Shoshan, and Sven Påhlman Mol. Cancer Ther., Jan 2009; 8: 160 - 170. |
| Journal: Cancer Research | Jan-09 |
| Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH Johanna Chiche, Karine Ilc, Julie Laferrière, Eric Trottier, Frédéric Dayan, Nathalie M. Mazure, M. Christiane Brahimi-Horn, and Jacques Pouysségur Cancer Res., Jan 2009; 69: 358 - 368. |
| Journal: Proceedings of the National Academy of Sciences | Jan-09 |
| DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses Sophie Vasseur, Samia Afzal, Joël Tardivel-Lacombe, David S. Park, Juan Lucio Iovanna, and Tak Wah Mak PNAS, Jan 2009; 106: 1111 - 1116. |
| Journal: Molecular Cancer Research | Jan-09 |
| Mutual Regulation of Hypoxia-Inducible Factor and Mammalian Target of Rapamycin as a Function of Oxygen Availability Karl X. Knaup, Katrin Jozefowski, Regina Schmidt, Wanja M. Bernhardt, Alexander Weidemann, Jan Steffen Juergensen, Christina Warnecke, Kai-Uwe Eckardt, and Michael S. Wiesener Mol. Cancer Res., Jan 2009; 7: 88 - 98. |
| Journal: Molecular and Cellular Biology | Dec-08 |
| Tumor Hypoxia Blocks Wnt Processing and Secretion through the Induction of Endoplasmic Reticulum Stress Meletios Verras, Ioanna Papandreou, Ai Lin Lim, and Nicholas C. Denko Mol. Cell. Biol., Dec 2008; 28: 7212 - 7224. |
| Journal: American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | Dec-08 |
| Placental HIFs as markers of cerebral hypoxic distress in fetal mice Regina Trollmann, Katja Strasser, Stephan Keller, Xenia Antoniou, Beat Grenacher, Omolara O. Ogunshola, Jörg Dötsch, Wolfgang Rascher, and Max Gassmann Am J Physiol Regulatory Integrative Comp Physiol, Dec 2008; 295: R1973 - R1981. |
| Journal: Molecular and Cellular Biology | Dec-08 |
| Hypoxia-Associated Factor, a Novel E3-Ubiquitin Ligase, Binds and Ubiquitinates Hypoxia-Inducible Factor 1, Leading to Its Oxygen-Independent Degradation Mei Yee Koh, Bryant G. Darnay, and Garth Powis Mol. Cell. Biol., Dec 2008; 28: 7081 - 7095. |
| Journal: Journal of Biological Chemistry | Dec-08 |
| The Histone Demethylases JMJD1A and JMJD2B Are Transcriptional Targets of Hypoxia-inducible Factor HIF Sophie Beyer, Malene Maag Kristensen, Kim Steen Jensen, Jens Vilstrup Johansen, and Peter Staller J. Biol. Chem., Dec 2008; 283: 36542 - 36552. |
| Journal: Carcinogenesis | Dec-08 |
| Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1-deficient mouse embryonic fibroblasts Renato Wirthner, Simon Wrann, Kuppusamy Balamurugan, Roland H. Wenger, and Daniel P. Stiehl Carcinogenesis, Dec 2008; 29: 2306 - 2316. |
| Journal: FASEB Journal | Dec-08 |
| Apelin/APJ signaling system: a potential link between adipose tissue and endothelial angiogenic processes O. Kunduzova, N. Alet, N. Delesque-Touchard, L. Millet, I. Castan-Laurell, C. Muller, C. Dray, P. Schaeffer, J. P. Herault, P. Savi, F. Bono, and P. Valet FASEB J, Dec 2008; 22: 4146 - 4153. |
| Journal: International Journal of Systematic and Evolutionary Microbiology | Dec-08 |
| Butyricicoccus pullicaecorum gen. nov., sp. nov., an anaerobic, butyrate-producing bacterium isolated from the caecal content of a broiler chicken Venessa Eeckhaut, Filip Van Immerseel, Emma Teirlynck, Frank Pasmans, Veerle Fievez, Cindy Snauwaert, Freddy Haesebrouck, Richard Ducatelle, Petra Louis, and Peter Vandamme Int J Syst Evol Microbiol, Dec 2008; 58: 2799 - 2802. |
| Journal: Cancer Research | Nov-08 |
| Hypoxia-Mediated Induction of the Polyamine System Provides Opportunities for Tumor Growth Inhibition by Combined Targeting of Vascular Endothelial Growth Factor and Ornithine Decarboxylase Katrin J. Svensson, Johanna E. Welch, Paulina Kucharzewska, Per Bengtson, Maria Bjurberg, Sven Påhlman, Gerdy B. Ten Dam, Lo Persson, and Mattias Belting Cancer Res., Nov 2008; 68: 9291 - 9301. |
| Journal: Journal of Biological Chemistry | Nov-08 |
| Nuclear Oxygen Sensing: Induction of Endogenous Prolyl-hydroxylase 2 Activity by Hypoxia and Nitric Oxide Utta Berchner-Pfannschmidt, Suzan Tug, Buena Trinidad, Felix Oehme, Hatice Yamac, Christoph Wotzlaw, Ingo Flamme, and Joachim Fandrey J. Biol. Chem., Nov 2008; 283: 31745 - 31753. |
| Journal: Cancer Research | Nov-08 |
| Preferential Cytotoxicity of Bortezomib toward Hypoxic Tumor Cells via Overactivation of Endoplasmic Reticulum Stress Pathways Diane R. Fels, Jiangbin Ye, Andrew T. Segan, Steven J. Kridel, Michael Spiotto, Michael Olson, Albert C. Koong, and Constantinos Koumenis Cancer Res., Nov 2008; 68: 9323 - 9330. |
| Journal: Molecular Cancer Therapeutics | Nov-08 |
| A RNA antagonist of hypoxia-inducible factor-1, EZN-2968, inhibits tumor cell growth Lee M. Greenberger, Ivan D. Horak, David Filpula, Puja Sapra, Majken Westergaard, Henrik F. Frydenlund, Charlotte Albæk, Henrik Schrøder, and Henrik Ørum Mol. Cancer Ther., Nov 2008; 7: 3598 - 3608. |
| Journal: Blood | Nov-08 |
| Divergent effects of hypoxia on dendritic cell functions Alessandra Mancino, Tiziana Schioppa, Paola Larghi, Fabio Pasqualini, Manuela Nebuloni, I-Hsuan Chen, Silvano Sozzani, Jonathan M. Austyn, Alberto Mantovani and Antonio Sica Blood, Nov 2008; 112: 3723-3734. |
| Journal: Journal of Biological Chemistry | Nov-08 |
| Hypoxic Reactive Oxygen Species Regulate the Integrated Stress Response and Cell Survival Liping Liu, David R. Wise, J. Alan Diehl, and M. Celeste Simon J. Biol. Chem., Nov 2008; 283: 31153 - 31162. |
| Journal: The Journal of Immunology | Oct-08 |
| Binding of Complement Inhibitor C4b-Binding Protein Contributes to Serum Resistance of Porphyromonas gingivalis Michal Potempa, Jan Potempa, Marcin Okroj, Katarzyna Popadiak, Sigrun Eick, Ky-Anh Nguyen, Kristian Riesbeck, and Anna M. Blom J. Immunol., Oct 2008; 181: 5537 - 5544. |
| Journal: Cardiovascular Research | Oct-08 |
| Diastolic dysfunction in alveolar hypoxia: a role for interleukin-18-mediated increase in protein phosphatase 2A Karl-Otto Larsen, Birgitte Lygren, Ivar Sjaastad, Kurt A. Krobert, Kristin Arnkværn, Geir Florholmen, Ann-Kristin Ruud Larsen, Finn Olav Levy, Kjetil Taskén, Ole Henning Skjønsberg, and Geir Christensen Cardiovasc Res, Oct 2008; 80: 47 - 54. |
| Journal: Cancer Research | Oct-08 |
| Noninvasive Molecular Imaging of Hypoxia in Human Xenografts: Comparing Hypoxia-Induced Gene Expression with Endogenous and Exogenous Hypoxia Markers Fuqiu He, Xuelong Deng, Bixiu Wen, Yueping Liu, Xiaorong Sun, Ligang Xing, Akiko Minami, Yunhong Huang, Qing Chen, Pat B. Zanzonico, C. Clifton Ling, and Gloria C. Li Cancer Res., Oct 2008; 68: 8597 - 8606. |
| Journal: Journal of Biological Chemistry | Oct-08 |
| Metabolic Stress Induces the Lysosomal Degradation of Neuropilin-1 but Not Neuropilin-2 Donggoo Bae, Shaolei Lu, Cherie A. Taglienti, and Arthur M. Mercurio J. Biol. Chem., Oct 2008; 283: 28074 - 28080. |
| Journal: Proceedings of the National Academy of Sciences | Oct-08 |
| The ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways Jianfei Qi, Koh Nakayama, Supriya Gaitonde, James S. Goydos, Stan Krajewski, Alexey Eroshkin, Dafna Bar-Sagi, David Bowtell, and Ze'ev Ronai PNAS, Oct 2008; 105: 16713 - 16718. |
| Journal: Applied and Environmental Microbiology | Sep-08 |
| Bond Strengthening in Oral Bacterial Adhesion to Salivary Conditioning Films Henny C. van der Mei, Minie Rustema-Abbing, Joop de Vries, and Henk J. Busscher Appl. Envir. Microbiol., Sep 2008; 74: 5511 - 5515. |
| Journal: Journal of the National Cancer Institute | Sep-08 |
| Induction of Apoptosis in Human Cancer Cells by Candidaspongiolide, a Novel Sponge Polyketide Daniela Trisciuoglio, Badarch Uranchimeg, John H. Cardellina, Tamara L. Meragelman, Shigeki Matsunaga, Nobuhiru Fusetani, Donatella Del Bufalo, Robert H. Shoemaker, and Giovanni Melillo J Natl Cancer Inst, Sep 2008; 100: 1233 - 1246. |
| Journal: American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | Sep-08 |
| Astrocyte responses to injury: VEGF simultaneously modulates cell death and proliferation Nicole Schmid-Brunclik, Carole Bürgi-Taboada, Xanthi Antoniou, Max Gassmann, and Omolara O. Ogunshola Am J Physiol Regulatory Integrative Comp Physiol, Sep 2008; 295: R864 - R873. |
| Journal: Journal of Endocrinology | Sep-08 |
| Phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3 and ERK1/2 pathways mediate protective effects of acylated and unacylated ghrelin against oxygen–glucose deprivation-induced apoptosis in primary rat cortical neuronal cells Hyunju Chung, Sanghee Seo, Minho Moon, and Seungjoon Park J. Endocrinol., Sep 2008; 198: 511 - 521. |
| Journal: Stem Cells | Aug-08 |
| Hypoxia Causes Downregulation of Mismatch Repair System and Genomic Instability in Stem Cells Francisco Javier Rodríguez-Jiménez, Victoria Moreno-Manzano, Rut Lucas-Dominguez, and José-María Sánchez-Puelles Stem Cells, Aug 2008; 26: 2052 - 2062. |
| Journal: American Journal of Physiology - Cell Physiology | Jul-08 |
| Hypoxia enhances lysosomal TNF- degradation in mouse peritoneal macrophages Nitza Lahat, Michal A. Rahat, Amalia Kinarty, Lea Weiss-Cerem, Sigalit Pinchevski, and Haim Bitterman Am J Physiol Cell Physiol, Jul 2008; 295: C2 - C12. |
| Journal: Molecular Pharmacology | Jul-08 |
| (2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide (BiPS), a Matrix Metalloprotease Inhibitor, Is a Novel and Potent Activator of Hypoxia-Inducible Factors Marie-Claude Lauzier, Geneviève A. Robitaille, Denise A. Chan, Amato J. Giaccia, and Darren E. Richard Mol. Pharmacol., Jul 2008; 74: 282 - 288. |
| Journal: Journal of Biological Chemistry | Jun-08 |
| Hypoxia-mediated Selective mRNA Translation by an Internal Ribosome Entry Site-independent Mechanism Regina M. Young, Shang-Jui Wang, John D. Gordan, Xinjun Ji, Stephen A. Liebhaber, and M. Celeste Simon J. Biol. Chem., Jun 2008; 283: 16309 - 16319. |
| Journal: Molecular Biology of the Cell | May-08 |
| Prolyl Hydroxylase PHD3 Activates Oxygen-dependent Protein Aggregation Krista Rantanen, Juha Pursiheimo, Heidi Högel, Virpi Himanen, Eric Metzen, and Panu M. Jaakkola Mol. Biol. Cell, May 2008; 19: 2231 - 2240. |
| Journal: Stem Cells | May-08 |
| Metabolic Flexibility Permits Mesenchymal Stem Cell Survival in an Ischemic Environment Louise A. Mylotte, Angela M. Duffy, Mary Murphy, Timothy O'Brien, Afshin Samali, Frank Barry, and Eva Szegezdi Stem Cells, May 2008; 26: 1325 - 1336. |
| Journal: Molecular Cancer Therapeutics | Apr-08 |
| Nutlin-3 radiosensitizes hypoxic prostate cancer cells independent of p53 Stéphane Supiot, Richard P. Hill, and Robert G. Bristow Mol. Cancer Ther., Apr 2008; 7: 993 - 999. |
| Journal: AACR Meeting Abstracts | Apr-08 |
| Re-oxygenation results in superior cell killing by an interleukin 13-cytotoxin than that of hypoxic glioblastoma multiforme cells Tiefu Liu, Jiaozhong Cai, Denise Gibo, and Waldemar Debinski AACR Meeting Abstracts, Apr 2008; 2008: 1522. |
| Journal: Circulation | Apr-08 |
| Absence of Cyclooxygenase-2 Exacerbates Hypoxia-Induced Pulmonary Hypertension and Enhances Contractility of Vascular Smooth Muscle Cells Laura E. Fredenburgh, Olin D. Liang, Alvaro A. Macias, Thomas R. Polte, Xiaoli Liu, Dario F. Riascos, Su Wol Chung, Scott L. Schissel, Donald E. Ingber, S. Alex Mitsialis, Stella Kourembanas, and Mark A. Perrella Circulation, Apr 2008; 117: 2114 - 2122. |
| Journal: International Journal of Systematic and Evolutionary Microbiology | Apr-08 |
| Lutispora thermophila gen. nov., sp. nov., a thermophilic, spore-forming bacterium isolated from a thermophilic methanogenic bioreactor digesting municipal solid wastes Hatsumi Shiratori, Hitomi Ohiwa, Hironori Ikeno, Shohei Ayame, Naoaki Kataoka, Akiko Miya, Teruhiko Beppu, and Kenji Ueda Int J Syst Evol Microbiol, Apr 2008; 58: 964 - 969. |
| Journal: Circulation Research | Apr-08 |
| Oxygen Deprivation Triggers Upregulation of Early Growth Response-1 by the Receptor for Advanced Glycation End Products Jong Sun Chang, Thoralf Wendt, Wu Qu, Linghua Kong, Yu Shan Zou, Ann Marie Schmidt, and Shi-Fang Yan Circ. Res., Apr 2008; 102: 905 - 913. |
| Journal: Molecular Cancer Research | Mar-08 |
| Metallothionein Induction by Hypoxia Involves Cooperative Interactions between Metal-Responsive Transcription Factor-1 and Hypoxia-Inducible Transcription Factor-1 Brian J. Murphy, Tomoki Kimura, Barbara G. Sato, Yihui Shi, and Glen K. Andrews Mol. Cancer Res., Mar 2008; 6: 483 - 490. |
| Journal: Proceedings of the National Academy of Sciences | Mar-08 |
| PHDs overactivation during chronic hypoxia "desensitizes" HIF and protects cells from necrosis Amandine Ginouvès, Karine Ilc, Nuria Macías, Jacques Pouysségur, and Edurne Berra PNAS, Mar 2008; 105: 4745 - 4750. |
| Journal: Molecular Biology of the Cell | Mar-08 |
| Prolyl Hydroxylase PHD3 Activates Oxygen-dependent Protein Aggregation Krista Rantanen, Juha Pursiheimo, Heidi Högel, Virpi Himanen, Eric Metzen, and Panu M. Jaakkola Mol. Biol. Cell, Mar 2008; 10.1091/mbc.E07-11-1124. |
| Journal: Clinical Cancer Research | Mar-08 |
| hsa-miR-210 Is Induced by Hypoxia and Is an Independent Prognostic Factor in Breast Cancer Carme Camps, Francesca M. Buffa, Stefano Colella, John Moore, Christos Sotiriou, Helen Sheldon, Adrian L. Harris, Jonathan M. Gleadle, and Jiannis Ragoussis Clin. Cancer Res., Mar 2008; 14: 1340 - 1348. |
| Journal: Circulation Research | Mar-08 |
| Oxygen Deprivation Triggers Upregulation of Early Growth Response-1 by the Receptor for Advanced Glycation End Products Jong Sun Chang, Thoralf Wendt, Wu Qu, Linghua Kong, Yu Shan Zou, Ann Marie Schmidt, and Shi-Fang Yan Circ. Res., Mar 2008; 10.1161/CIRCRESAHA.107.165308. |
| Journal: Proceedings of the National Academy of Sciences | Feb-08 |
| PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a) Brooke M. Emerling, Frank Weinberg, Juinn-Lin Liu, Tak W. Mak, and Navdeep S. Chandel PNAS, Feb 2008; 105: 2622 - 2627. |
| Journal: Stem Cells | Feb-08 |
| Metabolic Flexibility Permits MSC Survival in an Ischemic Environment Louise A. Mylotte, Angela M. Duffy, Mary Murphy, Timothy O'Brien, Afshin Samali, Frank Barry, and Eva Szegezdi Stem Cells, Feb 2008; 10.1634/stemcells.2007-1072. |
| Journal: Molecular Cancer Research | Feb-08 |
| Transcriptome of Hypoxic Immature Dendritic Cells: Modulation of Chemokine/Receptor Expression Annamaria Ricciardi, Angela Rita Elia, Paola Cappello, Maura Puppo, Cristina Vanni, Paolo Fardin, Alessandra Eva, David Munroe, Xiaolin Wu, Mirella Giovarelli, and Luigi Varesio Mol. Cancer Res., Feb 2008; 6: 175 - 185. |
| Journal: The New England Journal of Medicine | Jan-08 |
| A Gain-of-Function Mutation in the HIF2A Gene in Familial Erythrocytosis Melanie J. Percy, Paul W. Furlow, Guy S. Lucas, Xiping Li, Terence R.J. Lappin, Mary Frances McMullin, and Frank S. Lee N. Engl. J. Med., Jan 2008; 358: 162 - 168. |
| Journal: Cancer Research | Jan-08 |
| Differential Involvement of Vascular Endothelial Growth Factor in the Survival of Hypoxic Colon Cancer Cells Maura Calvani, Daniela Trisciuoglio, Cristina Bergamaschi, Robert H. Shoemaker, and Giovanni Melillo Cancer Res., Jan 2008; 68: 285 - 291. |
| Journal: Molecular Cancer Therapeutics | Jan-08 |
| Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1 Mei Y. Koh, Taly Spivak-Kroizman, Sara Venturini, Sarah Welsh, Ryan R. Williams, D. Lynn Kirkpatrick, and Garth Powis Mol. Cancer Ther., Jan 2008; 7: 90 - 100. |
| Journal: Molecular Biology of the Cell | Jan-08 |
| Hypoxia-inducible Factor-1 Stabilization in Nonhypoxic Conditions: Role of Oxidation and Intracellular Ascorbate Depletion Elisabeth L. Pagé, Denise A. Chan, Amato J. Giaccia, Mark Levine, and Darren E. Richard Mol. Biol. Cell, Jan 2008; 19: 86 - 94. |
| Journal: Molecular Biology of the Cell | Dec-07 |
| Hypoxia Up-Regulates Hypoxia-Inducible Factor-1 Transcription by Involving Phosphatidylinositol 3-Kinase and Nuclear Factor B in Pulmonary Artery Smooth Muscle Cells Rachida S. BelAiba, Steve Bonello, Christian Zähringer, Stefanie Schmidt, John Hess, Thomas Kietzmann, and Agnes Görlach Mol. Biol. Cell, Dec 2007; 18: 4691 - 4697. |
| Journal: FASEB Journal | Dec-07 |
| Hypoxia-mediated Na-K-ATPase degradation requires von Hippel Lindau protein Guofei Zhou, Laura A. Dada, Navdeep S. Chandel, Kazuhiro Iwai, Emilia Lecuona, Aaron Ciechanover, and Jacob I. Sznajder FASEB J, Dec 2007; 10.1096/fj.07-8369com. |
| Journal: Abstracts for theTwelfth Annual Meeting of the Society for Neuro-Oncology | Nov-07 |
| ET-46. RE-OXYGENATION OF HYPOXIC GLIOBLASTOMA MULTIFORME CELLS POTENTIATES KILLING EFFECT OF INTERLEUKIN 13–BASED CYTOTOXINS THROUGH RE-ESTABLISHMENT AND FURTHER UP-REGULATION OF IL13 RECEPTOR ALPHA2 Tiefu Liu, Jaiozhong Cai, Denise Gibo, and Waldemar Debinski Abstracts for theTwelfth Annual Meeting of the Society for Neuro-Oncology, November 15 –18, 2007 |
| Journal: American Journal of Pathology | Nov-07 |
| The Tumor Gene Survivin Is Highly Expressed in Adult Renal Tubular Cells: Implications for a Pathophysiological Role in the Kidney Philipp Lechler, Xiaoqing Wu, Wanja Bernhardt, Valentina Campean, Susanne Gastiger, Thomas Hackenbeck, Bernd Klanke, Alexander Weidemann, Christina Warnecke, Kerstin Amann, Dirk Engehausen, Carsten Willam, Kai-Uwe Eckardt, Franz Rödel, and Michael Sean Wiesener Am. J. Pathol., Nov 2007; 171: 1483 - 1498. |
| Journal: American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | Oct-07 |
| The HIF-1 response to simulated ischemia in mouse skeletal muscle cells neither enhances glycolysis nor prevents myotube cell death Nathalie Dehne, Uta Kerkweg, Teresa Otto, and Joachim Fandrey Am J Physiol Regulatory Integrative Comp Physiol, Oct 2007; 293: R1693 - R1701. |
| Journal: American Journal of Physiology - Renal Physiology | Oct-07 |
| Hypoxia and podocyte-specific Vhlh deletion confer risk of glomerular disease Kirsten Brukamp, Belinda Jim, Marcus J. Moeller, and Volker H. Haase Am J Physiol Renal Physiol, Oct 2007; 293: F1397 - F1407. |
| Journal: International Journal of Systematic and Evolutionary Microbiology | Oct-07 |
| Prevotella nanceiensis sp. nov., isolated from human clinical samples C. Alauzet, F. Mory, J.-P. Carlier, H. Marchandin, E. Jumas-Bilak, and A. Lozniewski Int J Syst Evol Microbiol, Oct 2007; 57: 2216 - 2220. |
| Journal: Journal of Biological Chemistry | Oct-07 |
| An Endoplasmic Reticulum Transmembrane Prolyl 4-Hydroxylase Is Induced by Hypoxia and Acts on Hypoxia-inducible Factor Peppi Koivunen, Päivi Tiainen, Jaana Hyvärinen, Kim E. Williams, Raija Sormunen, Stephen J. Klaus, Kari I. Kivirikko, and Johanna Myllyharju J. Biol. Chem., Oct 2007; 282: 30544 - 30552. |
| Journal: FASEB Journal | Oct-07 |
| Human hair follicles are an extrarenal source and a nonhematopoietic target of erythropoietin Eniko Bodó, Arno Kromminga, Wolfgang Funk, Magdalena Laugsch, Ute Duske, Wolfgang Jelkmann, and Ralf Paus FASEB J, Oct 2007; 21: 3346 - 3354. |
| Journal: Molecular and Cellular Biology | Aug-07 |
| Mitochondrial Reactive Oxygen Species Trigger Hypoxia-Inducible Factor-Dependent Extension of the Replicative Life Span during Hypoxia Eric L. Bell, Tatyana A. Klimova, James Eisenbart, Paul T. Schumacker, and Navdeep S. Chandel Mol. Cell. Biol., Aug 2007; 27: 5737 - 5745. |
| Journal: Endocrinology | Aug-07 |
| Differential Regulation of Hypoxia-Inducible Factor-1 through Receptor Tyrosine Kinase Transactivation in Vascular Smooth Muscle Cells Marie-Claude Lauzier, Elisabeth L. Pagé, Maude D. Michaud, and Darren E. Richard Endocrinology, Aug 2007; 148: 4023 - 4031. |
| Journal: American Journal of Physiology - Cell Physiology | Aug-07 |
| Normoxic stabilization of HIF-1 drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk Amit Agrawal, Asha Guttapalli, Srinivas Narayan, Todd J. Albert, Irving M. Shapiro, and Makarand V. Risbud Am J Physiol Cell Physiol, Aug 2007; 293: C621 - C631. |
| Journal: The Journal of Cell Biology | Jul-07 |
| The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production Eric L. Bell, Tatyana A. Klimova, James Eisenbart, Carlos T. Moraes, Michael P. Murphy, G.R. Scott Budinger, and Navdeep S. Chandel J. Cell Biol., Jul 2007; 177: 1029 - 1036. |
| Journal: The Journal of Bacteriology | Jul-07 |
| Conversion of Flavodoxin from Holoenzyme to Apoprotein during Growth Phase Changes in Helicobacter pylori Hirofumi Shimomura, Shunji Hayashi, Kenji Yokota, Keiji Oguma, and Yoshikazu Hirai J. Bacteriol., Jul 2007; 189: 4960 - 4963. |
| Journal: Journal of Endocrinology | Jul-07 |
| IGF-I inhibition of apoptosis is associated with decreased expression of prostate apoptosis response-4 Hyunju Chung, Sanghee Seo, Minho Moon, and Seungjoon Park J. Endocrinol., Jul 2007; 194: 77 - 85. |
| Journal: Journal of Cell Science | Jul-07 |
| Role of the small GTPase RhoA in the hypoxia-induced decrease of plasma membrane Na,K-ATPase in A549 cells Laura A. Dada, Eva Novoa, Emilia Lecuona, Haiying Sun, and Jacob I. Sznajder J. Cell Sci., Jul 2007; 120: 2214 - 2222. |
| Journal: The Journal of Immunology | Jun-07 |
| Biphasic Effect of Gingipains from Porphyromonas gingivalis on the Human Complement System Katarzyna Popadiak, Jan Potempa, Kristian Riesbeck, and Anna M. Blom J. Immunol., Jun 2007; 178: 7242 - 7250. |
| Journal: Journal of Dairy Science | Jun-07 |
| Development of New Probiotics by Strain Combinations: Is It Possible to Improve the Adhesion to Intestinal Mucus M. C. Collado, J. Meriluoto, and S. Salminen J Dairy Sci, Jun 2007; 90: 2710 - 2716. |
| Journal: Molecular and Cellular Biology | Jun-07 |
| Increased Activity of Hypoxia-Inducible Factor 1 Is Associated with Early Embryonic Lethality in Commd1 Null Mice Bart van de Sluis, Patricia Muller, Karen Duran, Amy Chen, Arjan J. Groot, Leo W. Klomp, Paul P. Liu, and Cisca Wijmenga Mol. Cell. Biol., Jun 2007; 27: 4142 - 4156. |
| Journal: Journal of Dental Research | May-07 |
| Sequence of Oral Bacterial Co-adhesion and Non-contact Brushing H.C. van der Mei, M. Rustema-Abbing, G.M. Bruinsma, B. Gottenbos, and H.J. Busscher J. Dent. Res., May 2007; 86: 421 - 425. |
| Journal: Stem Cells | May-07 |
| Severe Hypoxia Defines Heterogeneity and Selects Highly Immature Progenitors Within Clonal Erythroleukemia Cells Serena Giuntoli, Elisabetta Rovida, Antonella Gozzini, Valentina Barbetti, Maria Grazia Cipolleschi, Massimo Olivotto, and Persio Dello Sbarba Stem Cells, May 2007; 25: 1119 - 1125. |
| Journal: Proceedings of the National Academy of Sciences | May-07 |
| Metabolic targeting of hypoxia and HIF1 in solid tumors can enhance cytotoxic chemotherapy Rob A. Cairns, Ioanna Papandreou, Patrick D. Sutphin, and Nicholas C. Denko PNAS, May 2007; 104: 9445 - 9450. |
| Journal: International Journal of Radiation Biology | May-07 |
| Response of chronic hypoxic cells to low dose-rate irradiation EO Pettersen, I Bjorhovde, A Sovik, NF Edin, V Zachar, EO Hole, JA Sandvik, and P Ebbesen Int J Radiat Biol, May 2007; 83(5): 331-45. |
| Journal: Molecular Cancer Therapeutics | May-07 |
| Differential regulation of vascular endothelial growth factor by Akt and mammalian target of rapamycin inhibitors in cell lines derived from childhood solid tumors Raushan T. Kurmasheva, Franklin C. Harwood, and Peter J. Houghton Mol. Cancer Ther., May 2007; 6: 1620 - 1628. |
| Journal: Genes and Development | May-07 |
| The transcription factor HIF-1 plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis Julian J. Lum, Thi Bui, Michaela Gruber, John D. Gordan, Ralph J. DeBerardinis, Kelly L. Covello, M. Celeste Simon, and Craig B. Thompson Genes & Dev., May 2007; 21: 1037 - 1049. |
| Journal: Journal of Biological Chemistry | Mar-07 |
| Thioredoxin 1 and Thioredoxin 2 Have Opposed Regulatory Functions on Hypoxia-inducible Factor-1 Jie Zhou, Anastassios E. Damdimopoulos, Giannis Spyrou, and Bernhard Brüne J. Biol. Chem., Mar 2007; 282: 7482 - 7490. |
| Journal: Journal of Biological Chemistry | Mar-07 |
| Oxygen Tension Regulates the Stability of Insulin Receptor Substrate-1 (IRS-1) through Caspase-mediated Cleavage Sung Gyun Kang, Alexandra L. Brown, and Jay H. Chung J. Biol. Chem., Mar 2007; 282: 6090 - 6097. |
| Journal: FASEB Journal | Mar-07 |
| Optical analysis of the HIF-1 complex in living cells by FRET and FRAP Christoph Wotzlaw, Teresa Otto, Utta Berchner-Pfannschmidt, Eric Metzen, Helmut Acker, and Joachim Fandrey FASEB J, Mar 2007; 21: 700 - 707. |
| Journal: Molecular and Cellular Biology | Mar-07 |
| A MicroRNA Signature of Hypoxia Ritu Kulshreshtha, Manuela Ferracin, Sylwia E. Wojcik, Ramiro Garzon, Hansjuerg Alder, Francisco J. Agosto-Perez, Ramana Davuluri, Chang-Gong Liu, Carlo M. Croce, Massimo Negrini, George A. Calin, and Mircea Ivan Mol. Cell. Biol., Mar 2007; 27: 1859 - 1867. |
| Journal: Molecular and Cellular Biology | Feb-07 |
| Loss of Mcl-1 Protein and Inhibition of Electron Transport Chain Together Induce Anoxic Cell Death Joslyn K. Brunelle, Emelyn H. Shroff, Harris Perlman, Andreas Strasser, Carlos T. Moraes, Richard A. Flavell, Nika N. Danial, Brian Keith, Craig B. Thompson, and Navdeep S. Chandel Mol. Cell. Biol., Feb 2007; 27: 1222 - 1235. |
| Journal: Clinical Cancer Research | Feb-07 |
| Cell Type–Specific, Topoisomerase II–Dependent Inhibition of Hypoxia-Inducible Factor-1 Protein Accumulation by NSC 644221 Mark Creighton-Gutteridge, John H. Cardellina, II, Andrew G. Stephen, Annamaria Rapisarda, Badarch Uranchimeg, Karen Hite, William A. Denny, Robert H. Shoemaker, and Giovanni Melillo Clin. Cancer Res., Feb 2007; 13: 1010 - 1018. |
| Journal: Molecular and Cellular Biology | Feb-07 |
| Multiple Factors Affecting Cellular Redox Status and Energy Metabolism Modulate Hypoxia-Inducible Factor Prolyl Hydroxylase Activity In Vivo and In Vitro Yi Pan, Kyle D. Mansfield, Cara C. Bertozzi, Viktoriya Rudenko, Denise A. Chan, Amato J. Giaccia, and M. Celeste Simon Mol. Cell. Biol., Feb 2007; 27: 912 - 925. |
| Journal: Journal of Biological Chemistry | Jan-07 |
| Nitric Oxide Modulates Oxygen Sensing by Hypoxia-inducible Factor 1-dependent Induction of Prolyl Hydroxylase 2 Utta Berchner-Pfannschmidt, Hatice Yamac, Buena Trinidad, and Joachim Fandrey J. Biol. Chem., Jan 2007; 282: 1788 - 1796. |
| Journal: Cancer Research | Jan-07 |
| Adenovirus-Mediated Expression of a Dominant Negative Ku70 Fragment Radiosensitizes Human Tumor Cells under Aerobic and Hypoxic Conditions Fuqiu He, Ligeng Li, Dooha Kim, Bixiu Wen, Xuelong Deng, Philip H. Gutin, Clifton C. Ling, and Gloria C. Li Cancer Res., Jan 2007; 67: 634 - 642. |
| Journal: Endocrinology | Jan-07 |
| Ghrelin Inhibits Apoptosis in Hypothalamic Neuronal Cells during Oxygen-Glucose Deprivation Hyunju Chung, Eunhee Kim, Dae Hee Lee, Sanghee Seo, Sunghee Ju, Dahm Lee, Hocheol Kim, and Seungjoon Park Endocrinology, Jan 2007; 148: 148 - 159. |
| Journal: Applied and Environmental Microbiology | Jan-07 |
| Respiration and Growth of Shewanella decolorationis S12 with an Azo Compound as the Sole Electron Acceptor Yiguo Hong, Meiying Xu, Jun Guo, Zhicheng Xu, Xingjuan Chen, and Guoping Sun Appl. Envir. Microbiol., Jan 2007; 73: 64 - 72. |
| Journal: Genes and Development | Dec-06 |
| HIF1 delays premature senescence through the activation of MIF Scott M. Welford, Barbara Bedogni, Katarina Gradin, Lorenz Poellinger, Marianne Broome Powell, and Amato J. Giaccia Genes & Dev., Dec 2006; 20: 3366 - 3371. |
| Journal: Cancer Research | Dec-06 |
| Antitumor Effect of 2-Methoxyestradiol in a Rat Orthotopic Brain Tumor Model Seung-Hee Kang, Heidi T. Cho, Sarojini Devi, Zhaobin Zhang, Daniel Escuin, Zhongxing Liang, Hui Mao, Daniel J. Brat, Jeffrey J. Olson, Jonathan W. Simons, Theresa M. LaVallee, Paraskevi Giannakakou, Erwin G. Van Meir, and Hyunsuk Shim Cancer Res., Dec 2006; 66: 11991 - 11997. |
| Journal: Journal of Biological Chemistry | Nov-06 |
| Regulation of the Ring Finger E3 Ligase Siah2 by p38 MAPK Ashwani Khurana, Koh Nakayama, Scott Williams, Roger J. Davis, Tomas Mustelin, and Ze'ev Ronai J. Biol. Chem., Nov 2006; 281: 35316 - 35326. |
| Journal: Journal of Biological Chemistry | Oct-06 |
| Differentiation Arrest by Hypoxia Qun Lin, Yi-Jang Lee, and Zhong Yun J. Biol. Chem., Oct 2006; 281: 30678 - 30683. |
| Journal: Nucleic Acids Research | Sep-06 |
| Wnt-5a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells Karin Leandersson, Kristian Riesbeck, and Tommy Andersson Nucleic Acids Res., Sep 2006; 34: 3988 - 3999. |
| Journal: Molecular Cancer Therapeutics | Sep-06 |
| Chronic hypoxia promotes hypoxia-inducible factor-1–dependent resistance to etoposide and vincristine in neuroblastoma cells Deema Hussein, Edward J. Estlin, Caroline Dive, and Guy W.J. Makin Mol. Cancer Ther., Sep 2006; 5: 2241 - 2250. |
| Journal: Circulation Research | Aug-06 |
| Hypoxia Regulates Bone Morphogenetic Protein Signaling Through C-Terminal–Binding Protein 1 Xinqi Wu, Mun Seog Chang, S. Alex Mitsialis, and Stella Kourembanas Circ. Res., Aug 2006; 99: 240 - 247. |
| Journal: Journal of Biological Chemistry | Aug-06 |
| Increased Prolyl 4-Hydroxylase Domain Proteins Compensate for Decreased Oxygen Levels: EVIDENCE FOR AN AUTOREGULATORY OXYGEN-SENSING SYSTEM Daniel P. Stiehl, Renato Wirthner, Jens Köditz, Patrick Spielmann, Gieri Camenisch, and Roland H. Wenger J. Biol. Chem., Aug 2006; 281: 23482 - 23491. |
| Journal: American Journal of Respiratory Cell and Molecular Biology | Jul-06 |
| Phosphorylation of Adaptor Protein–2 µ2 Is Essential for Na+,K+-ATPase Endocytosis in Response to Either G Protein–Coupled Receptor or Reactive Oxygen Species Zongpei Chen, Rafael T. Krmar, Laura Dada, Riad Efendiev, Ingo B. Leibiger, Carlos H. Pedemonte, Adrian I. Katz, Jacob I. Sznajder, and Alejandro M. Bertorello Am. J. Respir. Cell Mol. Biol., Jul 2006; 35: 127 - 132. |
| Journal: Journal of Biological Chemistry | Jul-06 |
| ß-Adrenergic Receptor Stimulation and Adenoviral Overexpression of Superoxide Dismutase Prevent the Hypoxia-mediated Decrease in Na,K-ATPase and Alveolar Fluid Reabsorption Juan Litvan, Arturo Briva, Mindy S. Wilson, G. R. Scott Budinger, Jacob Iasha Sznajder, and Karen M. Ridge J. Biol. Chem., Jul 2006; 281: 19892 - 19898. |
| Journal: Journal of Biological Chemistry | May-06 |
| Histone Deacetylase Inhibitors Repress the Transactivation Potential of Hypoxia-inducible Factors Independently of Direct Acetylation of HIF- Donna M. Fath, Xianguo Kong, Dongming Liang, Zhao Lin, Andrew Chou, Yubao Jiang, Jie Fang, Jaime Caro, and Nianli Sang J. Biol. Chem., May 2006; 281: 13612 - 13619. |
| Journal: Circulation Research | May-06 |
| Hypoxia-Mediated Degradation of Na,K-ATPase via Mitochondrial Reactive Oxygen Species and the Ubiquitin-Conjugating System Alejandro P. Comellas, Laura A. Dada, Emilia Lecuona, Liuska M. Pesce, Navdeep S. Chandel, Nancy Quesada, G. R. Scott Budinger, Ger J. Strous, Aaron Ciechanover, and Jacob I. Sznajder Circ. Res., May 2006; 98: 1314 - 1322. |
| Journal: Molecular Biology of the Cell | Apr-06 |
| Calpain Mediates a von Hippel-Lindau Protein–independent Destruction of Hypoxia-inducible Factor-1 Jie Zhou, Roman Köhl, Barbara Herr, Ronald Frank, and Bernhard Brüne Mol. Biol. Cell, Apr 2006; 17: 1549 - 1558. |
| Journal: Molecular and Cellular Biology | Apr-06 |
| Sterol Regulatory Element Binding Protein Is a Principal Regulator of Anaerobic Gene Expression in Fission Yeast Bridget L. Todd, Emerson V. Stewart, John S. Burg, Adam L. Hughes, and Peter J. Espenshade Mol. Cell. Biol., Apr 2006; 26: 2817 - 2831. |
| Journal: Cancer Research | Apr-06 |
| Regulation of E-cadherin Expression by VHL and Hypoxia-Inducible Factor Miguel A. Esteban, Maxine G.B. Tran, Sarah K. Harten, Peter Hill, Maria C. Castellanos, Ashish Chandra, Raju Raval, Tim S. O'Brien, and Patrick H. Maxwell Cancer Res., Apr 2006; 66: 3567 - 3575. |
| Journal: Cancer Research | Apr-06 |
| The Oxygen Sensor Factor-Inhibiting Hypoxia-Inducible Factor-1 Controls Expression of Distinct Genes through the Bifunctional Transcriptional Character of Hypoxia-Inducible Factor-1 Frédéric Dayan, Danièle Roux, M. Christiane Brahimi-Horn, Jacques Pouyssegur, and Nathalie M. Mazure Cancer Res., Apr 2006; 66: 3688 - 3698. |
| Journal: Blood | Apr-06 |
| Hypoxic induction of an HIF-1–dependent bFGF autocrine loop drives angiogenesis in human endothelial cells Maura Calvani, Annamaria Rapisarda, Badarch Uranchimeg, Robert H. Shoemaker, and Giovanni Melillo Blood, Apr 2006; 107: 2705 - 2712. |
| Journal: Endocrinology | Mar-06 |
| Adrenomedullin Regulates Cellular Glutathione Content via Modulation of -Glutamate-Cysteine Ligase Catalytic Subunit Expression Jee-Youn Kim, Ji-Hye Yim, Jin-Ho Cho, Jin-Hwan Kim, Jeong-Hun Ko, Su-Mi Kim, Seungjoon Park, and Jae-Hoon Park Endocrinology, Mar 2006; 147: 1357 - 1364. |
| Journal: Journal of Dental Research | Mar-06 |
| Interactive Forces between Co-aggregating and Non-co-aggregating Oral Bacterial Pairs F. Postollec, W. Norde, J. de Vries, H.J. Busscher, and H.C. van der Mei J. Dent. Res., Mar 2006; 85: 231 - 234. |
| Journal: Clinical Cancer Research | Feb-06 |
| Overexpression and Nuclear Translocation of Hypoxia-Inducible Factor Prolyl Hydroxylase PHD2 in Head and Neck Squamous Cell Carcinoma Is Associated with Tumor Aggressiveness Terhi Jokilehto, Krista Rantanen, Marjaana Luukkaa, Pekka Heikkinen, Reidar Grenman, Heikki Minn, Pauliina Kronqvist, and Panu M. Jaakkola Clin. Cancer Res., Feb 2006; 12: 1080 - 1087. |
| Journal: Cancer Research | Feb-06 |
| von Hippel-Lindau Tumor Suppressor Protein Regulates the Assembly of Intercellular Junctions in Renal Cancer Cells through Hypoxia-Inducible Factor–Independent Mechanisms Maria J. Calzada, Miguel A. Esteban, Monica Feijoo-Cuaresma, Maria C. Castellanos, Salvador Naranjo-Suárez, Elisa Temes, Fernando Méndez, Maria Yánez-Mo, Michael Ohh, and Manuel O. Landázuri Cancer Res., Feb 2006; 66: 1553 - 1560. |
| Journal: Cancer Research | Jan-06 |
| Activation of RhoB by Hypoxia Controls Hypoxia-Inducible Factor-1 Stabilization through Glycogen Synthase Kinase-3 in U87 Glioblastoma Cells Nicolas Skuli, Sylvie Monferran, Caroline Delmas, Isabelle Lajoie-Mazenc, Gilles Favre, Christine Toulas, and Elizabeth Cohen-Jonathan-Moyal Cancer Res., Jan 2006; 66: 482 - 489. |
| Journal: Proceedings of the National Academy of Sciences | Jan-06 |
| From the Cover: Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production Michal Safran, William Y. Kim, Fionnuala O'Connell, Lee Flippin, Volkmar Günzler, James W. Horner, Ronald A. DePinho, and William G. Kaelin, Jr. PNAS, Jan 2006; 103: 105 - 110. |
| Journal: Cancer Research | Dec-05 |
| Hypoxia-Induced Phosphorylation of Chk2 in an Ataxia Telangiectasia Mutated–Dependent Manner Shannon L. Gibson, Ranjit S. Bindra, and Peter M. Glazer Cancer Res., Dec 2005; 65: 10734 - 10741. |
| Journal: American Journal of Physiology - Renal Physiology | Dec-05 |
| Protection of HIF-1-deficient primary renal tubular epithelial cells from hypoxia-induced cell death is glucose dependent Mangatt P. Biju, Yasuhiro Akai, Nikita Shrimanker, and Volker H. Haase Am J Physiol Renal Physiol, Dec 2005; 289: F1217 - F1226. |
| Journal: International Journal of Systematic and Evolutionary Microbiology | Nov-05 |
| Thermococcus coalescens sp. nov., a cell-fusing hyperthermophilic archaeon from Suiyo Seamount Tomohiko Kuwabara, Masaomi Minaba, Yukihiro Iwayama, Isao Inouye, Miwako Nakashima, Katsumi Marumo, Akihiko Maruyama, Akihiko Sugai, Toshihiro Itoh, Jun-ichiro Ishibashi, Tetsuro Urabe, and Masahiro Kamekura Int J Syst Evol Microbiol, Nov 2005; 55: 2507 - 2514. |
| Journal: Blood | Oct-05 |
| Inhibition of mitochondrial respiration elevates oxygen concentration but leaves regulation of hypoxia-inducible factor (HIF) intact Kathrin Doege, Sandra Heine, Inga Jensen, Wolfgang Jelkmann, and Eric Metzen Blood, Oct 2005; 106: 2311 - 2317. |
| Journal: Journal of the American Society of Nephrology | Oct-05 |
| Hypoxia Increases Group IIA Phospholipase A2 Expression under Inflammatory Conditions in Rat Renal Mesangial Cells Claudia Petry, Andrea Huwiler, Wolfgang Eberhardt, Marietta Kaszkin, and Josef Pfeilschifter J. Am. Soc. Nephrol., Oct 2005; 16: 2897 - 2905. |
| Journal: American Journal of Respiratory Cell and Molecular Biology | Oct-05 |
| Heterotrimeric G Proteins and the Platelet-Derived Growth Factor Receptor-ß Contribute to Hypoxic Proliferation of Smooth Muscle Cells M. Carita Lannér, Maggie Raper, Whitney M. Pratt, and Rodney A. Rhoades Am. J. Respir. Cell Mol. Biol., Oct 2005; 33: 412 - 419. |
| Journal: Journal of Biological Chemistry | Sep-05 |
| Arrest-defective-1 Protein, an Acetyltransferase, Does Not Alter Stability of Hypoxia-inducible Factor (HIF)-1 and Is Not Induced by Hypoxia or HIF Rebecca Bilton, Nathalie Mazure, Eric Trottier, Maurice Hattab, Marc-André Déry, Darren E. Richard, Jacques Pouysségur, and M. Christiane Brahimi-Horn J. Biol. Chem., Sep 2005; 280: 31132 - 31140. |
| Journal: The Journal of Neuroscience | Sep-05 |
| Overexpression of PrPC by Adenovirus-Mediated Gene Targeting Reduces Ischemic Injury in a Stroke Rat Model Woei-Cherng Shyu, Shinn-Zong Lin, Ming-Fu Chiang, Dah-Ching Ding, Kuo-Wei Li, Shih-Fen Chen, Hui-I Yang, and Hung Li J. Neurosci., Sep 2005; 25: 8967 - 8977. |
| Journal: Molecular and Cellular Biology | Aug-05 |
| Coordinate Regulation of the Oxygen-Dependent Degradation Domains of Hypoxia-Inducible Factor 1 Denise A. Chan, Patrick D. Sutphin, Shing-Erh Yen, and Amato J. Giaccia Mol. Cell. Biol., Aug 2005; 25: 6415 - 6426. |
| Journal: Applied and Environmental Microbiology | Jul-05 |
| Influence of Fluid Shear and Microbubbles on Bacterial Detachment from a Surface Prashant K. Sharma, Marjon J. Gibcus, Henny C. van der Mei, and Henk J. Busscher Appl. Envir. Microbiol., Jul 2005; 71: 3668 - 3673. |
| Journal: Molecular Cancer Therapeutics | Jul-05 |
| Multidrug-resistant neuroblastoma cells are responsive to arsenic trioxide at both normoxia and hypoxia Jenny Karlsson, Anders Edsjö, Sven Påhlman, and Helen M. Pettersson Mol. Cancer Ther., Jul 2005; 4: 1128 - 1135. |
| Journal: Molecular and Cellular Biology | Jun-05 |
| Mitochondrial Reactive Oxygen Species Activation of p38 Mitogen-Activated Protein Kinase Is Required for Hypoxia Signaling Brooke M. Emerling, Leonidas C. Platanias, Emma Black, Angel R. Nebreda, Roger J. Davis, and Navdeep S. Chandel Mol. Cell. Biol., Jun 2005; 25: 4853 - 4862. |
| Journal: Journal of Biological Chemistry | Jun-05 |
| Activation of HIF-prolyl Hydroxylases by R59949, an Inhibitor of the Diacylglycerol Kinase Elisa Temes, Silvia Martín-Puig, Bárbara Acosta-Iborra, Maria C. Castellanos, Mónica Feijoo-Cuaresma, Gemma Olmos, Julián Aragonés, and Manuel O. Landázuri J. Biol. Chem., Jun 2005; 280: 24238 - 24244. |
| Journal: Molecular and Cellular Biology | Jun-05 |
| Decreased Growth of Vhl–/– Fibrosarcomas Is Associated with Elevated Levels of Cyclin Kinase Inhibitors p21 and p27 Fiona A. Mack, Jagruti H. Patel, Mangatt P. Biju, Volker H. Haase, and M. Celeste Simon Mol. Cell. Biol., Jun 2005; 25: 4565 - 4578. |
| Journal: Blood | Jun-05 |
| Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation Falk Martin, Tobias Linden, Dörthe M. Katschinski, Felix Oehme, Ingo Flamme, Chinmay K. Mukhopadhyay, Katrin Eckhardt, Juliane Tröger, Sandra Barth, Gieri Camenisch, and Roland H. Wenger Blood, Jun 2005; 105: 4613 - 4619. |
| Journal: Annals of the New York Academy of Sciences | May-05 |
| Protective Effect of -Keto-ß-Methyl-n-Valeric Acid on BV-2 Microglia under Hypoxia or Oxidative Stress HSUEH-MEEI HUANG, HSIO-CHUNG OU, HUAN-LIAN CHEN, ROLIS CHIEN-WEI HOU, and KEE CHING G. JENG Ann. N.Y. Acad. Sci., May 2005; 1042: 272 - 278. |
| Journal: Cancer Research | Apr-05 |
| Anoxia Is Necessary for Tumor Cell Toxicity Caused by a Low-Oxygen Environment Ioanna Papandreou, Chaya Krishna, Fiona Kaper, Deli Cai, Amato J. Giaccia, and Nicholas C. Denko Cancer Res., Apr 2005; 65: 3171 - 3178. |
| Journal: Molecular and Cellular Biology | Apr-05 |
| Adaptive Myogenesis under Hypoxia Zhong Yun, Qun Lin, and Amato J. Giaccia Mol. Cell. Biol., Apr 2005; 25: 3040 - 3055. |
| Journal: American Journal of Physiology - Renal Physiology | Dec-04 |
| Hypoxic induction of Ctgf is directly mediated by Hif-1 Debra F. Higgins, Mangatt P. Biju, Yasuhiro Akai, Anton Wutz, Randall S. Johnson, and Volker H. Haase Am J Physiol Renal Physiol, Dec 2004; 287: F1223 - F1232. |
| Journal: Genes and Development | Dec-04 |
| Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex James Brugarolas, Kui Lei, Rebecca L. Hurley, Brendan D. Manning, Jan H. Reiling, Ernst Hafen, Lee A. Witters, Leif W. Ellisen, and William G. Kaelin, Jr. Genes & Dev., Dec 2004; 18: 2893 - 2904. |
| Journal: The Journal of Neuroscience | Nov-04 |
| Hypoxia-Ischemia Induces DNA Synthesis without Cell Proliferation in Dying Neurons in Adult Rodent Brain Chia-Yi Kuan, Aryn J. Schloemer, Aigang Lu, Kevin A. Burns, Wei-Lan Weng, Michael T. Williams, Kenneth I. Strauss, Charles V. Vorhees, Richard A. Flavell, Roger J. Davis, Frank R. Sharp, and Pasko Rakic J. Neurosci., Nov 2004; 24: 10763 - 10772. |
| Journal: The Journal of Virology | Oct-04 |
| Human Cytomegalovirus Infection Induces Rapamycin-Insensitive Phosphorylation of Downstream Effectors of mTOR Kinase Sagar B. Kudchodkar, Yongjun Yu, Tobi G. Maguire, and James C. Alwine J. Virol., Oct 2004; 78: 11030 - 11039. |
| Journal: Journal of Applied Physiology | Oct-04 |
| Hypoxic reduction in cellular glutathione levels requires mitochondrial reactive oxygen species Kyle D. Mansfield, M. Celeste Simon, and Brian Keith J Appl Physiol, Oct 2004; 97: 1358 - 1366. |
| Journal: Cancer Research | Oct-04 |
| Schedule-dependent Inhibition of Hypoxia-inducible Factor-1 Protein Accumulation, Angiogenesis, and Tumor Growth by Topotecan in U251-HRE Glioblastoma Xenografts Annamaria Rapisarda, Jessica Zalek, Melinda Hollingshead, Till Braunschweig, Badarch Uranchimeg, Carrie A. Bonomi, Suzanne D. Borgel, John P. Carter, Stephen M. Hewitt, Robert H. Shoemaker, and Giovanni Melillo Cancer Res., Oct 2004; 64: 6845 - 6848. |
| Journal: Journal of Biological Chemistry | Oct-04 |
| Genetic Analysis of the Role of the Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-inducible Factor (HIF) in Regulating HIF Transcriptional Target Genes Ineke P. Stolze, Ya-Min Tian, Rebecca J. Appelhoff, Helen Turley, Charles C. Wykoff, Jonathan M. Gleadle, and Peter J. Ratcliffe J. Biol. Chem., Oct 2004; 279: 42719 - 42725. |
| Journal: Journal of Biological Chemistry | Sep-04 |
| Mitochondrial Reactive Oxygen Species Control the Transcription Factor CHOP-10/GADD153 and Adipocyte Differentiation: A MECHANISM FOR HYPOXIA-DEPENDENT EFFECT Audrey Carrière, Maria-Carmen Carmona, Yvette Fernandez, Michel Rigoulet, Roland H. Wenger, Luc Pénicaud, and Louis Casteilla J. Biol. Chem., Sep 2004; 279: 40462 - 40469. |
| Journal: Journal of Biological Chemistry | Sep-04 |
| Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor Rebecca J. Appelhoff, Ya-Min Tian, Raju R. Raval, Helen Turley, Adrian L. Harris, Christopher W. Pugh, Peter J. Ratcliffe, and Jonathan M. Gleadle J. Biol. Chem., Sep 2004; 279: 38458 - 38465. |
| Journal: Journal of Biological Chemistry | Sep-04 |
| Transient Changes in Oxygen Tension Inhibit Osteogenic Differentiation and Runx2 Expression in Osteoblasts Ali Salim, Randall P. Nacamuli, Elise F. Morgan, Amato J. Giaccia, and Michael T. Longaker J. Biol. Chem., Sep 2004; 279: 40007 - 40016. |
| Journal: Applied and Environmental Microbiology | Jul-04 |
| New Real-Time Quantitative PCR Procedure for Quantification of Bifidobacteria in Human Fecal Samples Miguel Gueimonde, Satu Tölkkö, Teemu Korpimäki, and Seppo Salminen Appl. Envir. Microbiol., Jul 2004; 70: 4165 - 4169. |
| Journal: Journal of Biological Chemistry | Jun-04 |
| The Stem Cell Marker Bcrp/ABCG2 Enhances Hypoxic Cell Survival through Interactions with Heme Partha Krishnamurthy, Douglas D. Ross, Takeo Nakanishi, Kim Bailey-Dell, Sheng Zhou, Kelly E. Mercer, Balazs Sarkadi, Brian P. Sorrentino, and John D. Schuetz J. Biol. Chem., Jun 2004; 279: 24218 - 24225. |
| Journal: Journal of Biological Chemistry | May-04 |
| Follicle-stimulating Hormone Activation of Hypoxia-inducible Factor-1 by the Phosphatidylinositol 3-Kinase/AKT/Ras Homolog Enriched in Brain (Rheb)/Mammalian Target of Rapamycin (mTOR) Pathway Is Necessary for Induction of Select Protein Markers of Follicular Differentiation Hena Alam, Evelyn T. Maizels, Youngkyu Park, Shail Ghaey, Zachary J. Feiger, Navdeep S. Chandel, and Mary Hunzicker-Dunn J. Biol. Chem., May 2004; 279: 19431 - 19440. |
| Journal: Cancer Research | May-04 |
| Akt and Hypoxia-Inducible Factor-1 Independently Enhance Tumor Growth and Angiogenesis Andrew M. Arsham, David R. Plas, Craig B. Thompson, and M. Celeste Simon Cancer Res., May 2004; 64: 3500 - 3507. |
| Journal: Blood | Mar-04 |
| Anoxic induction of ATF-4 through HIF-1–independent pathways of protein stabilization in human cancer cells Kurosh Ameri, Claire E. Lewis, Martin Raida, Heidi Sowter, Tsonwin Hai, and Adrian L. Harris Blood, Mar 2004; 103: 1876 - 1882. |
| Journal: Journal of Biological Chemistry | Mar-04 |
| Role of Iron (II)-2-Oxoglutarate-dependent Dioxygenases in the Generation of Hypoxia-induced Phosphatidic Acid through HIF-1/2 and von Hippel-Lindau-independent Mechanisms Silvia Martín-Puig, Elisa Temes, Gemma Olmos, David R. Jones, Julián Aragonés, and Manuel O. Landázuri J. Biol. Chem., Mar 2004; 279: 9504 - 9511. |
| Journal: AACR Meeting Abstracts | Mar-04 |
| The influence of hypoxia in promoting malignant progression in prostate cancer cells Karl Butterworth, Helen O. McCarthy, Tracy Robson, and Stephanie McKeown AACR Meeting Abstracts, Mar 2004; 2004: 789. |
| Journal: Journal of Biological Chemistry | Feb-04 |
| c-Myc Sensitization to Oxygen Deprivation-induced Cell Death Is Dependent on Bax/Bak, but Is Independent of p53 and Hypoxia-inducible Factor-1 Joslyn K. Brunelle, Matthew T. Santore, G. R. Scott Budinger, Yueming Tang, Terrence A. Barrett, Wei-Xing Zong, Eugene Kandel, Brian Keith, M. Celeste Simon, Craig B. Thompson, Nissim Hay, and Navdeep S. Chandel J. Biol. Chem., Feb 2004; 279: 4305 - 4312. |
| Journal: Blood | Feb-04 |
| Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1 Caroline C. Blouin, Elisabeth L. Pagé, Guylaine M. Soucy, and Darren E. Richard Blood, Feb 2004; 103: 1124 - 1130. |
| Journal: Microbiology | Jan-04 |
| Metronidazole induces programmed cell death in the protozoan parasite Blastocystis hominis A. M. A. Nasirudeen, Yap Eu Hian, Mulkit Singh, and Kevin S. W. Tan Microbiology, Jan 2004; 150: 33. |
| Journal: Clinical Cancer Research | Dec-03 |
| The Farnesyltransferase Inhibitor R115777 Reduces Hypoxia and Matrix Metalloproteinase 2 Expression in Human Glioma Xenograft Caroline Delmas, Dave End, Philippe Rochaix, Gilles Favre, Christine Toulas, and Elizabeth Cohen-Jonathan Clin. Cancer Res., Dec 2003; 9: 6062 - 6068. |
| Journal: Journal of Biological Chemistry | Dec-03 |
| The von Hippel Lindau/Hypoxia-inducible Factor (HIF) Pathway Regulates the Transcription of the HIF-Proline Hydroxylase Genes in Response to Low Oxygen Luis del Peso, María C. Castellanos, Elisa Temes, Silvia Martín-Puig, Yolanda Cuevas, Gemma Olmos, and Manuel O. Landázuri J. Biol. Chem., Dec 2003; 278: 48690 - 48695. |
| Journal: Cancer Research | Oct-03 |
| Specific Oncolytic Effect of a New Hypoxia-Inducible Factor-Dependent Replicative Adenovirus on von Hippel-Lindau-Defective Renal Cell Carcinomas Yolanda Cuevas, Rubén Hernández-Alcoceba, Julian Aragones, Salvador Naranjo-Suárez, María C. Castellanos, Miguel A. Esteban, Silvia Martín-Puig, Manuel O. Landazuri, and Luis del Peso Cancer Res., Oct 2003; 63: 6877 - 6884. |
| Journal: The Journal of Immunology | Sep-03 |
| Hypoxia Inactivates Inducible Nitric Oxide Synthase in Mouse Macrophages by Disrupting Its Interaction with -Actinin 4 Sharon Daniliuc, Haim Bitterman, Michal A. Rahat, Amalia Kinarty, Doron Rosenzweig, and Lahat Nitza J. Immunol., Sep 2003; 171: 3225 - 3232. |
| Journal: Molecular and Cellular Biology | Sep-03 |
| Differential roles of HIF-1 and HIF-2 in hypoxic gene regulation Hu, C.-J., L.-Y. Wang, L. A. Chodosh, B. Keith, and M. C. Simon Mol. Cell Biol., Sep 2003; 23: 9361 - 9374. |
| Journal: Molecular Biology of the Cell | Aug-03 |
| Nitric Oxide Impairs Normoxic Degradation of HIF-1 by Inhibition of Prolyl Hydroxylases Eric Metzen, Jie Zhou, Wolfgang Jelkmann, Joachim Fandrey, and Bernhard Brüne Mol. Biol. Cell, Aug 2003; 14: 3470 - 3481. |
| Journal: Journal of Biological Chemistry | Aug-03 |
| A Novel Hypoxia-inducible Factor-independent Hypoxic Response Regulating Mammalian Target of Rapamycin and Its Targets Andrew M. Arsham, Jessica J. Howell, and M. Celeste Simon J. Biol. Chem., Aug 2003; 278: 29655 - 29660. |
| Journal: Journal of Biological Chemistry | Apr-03 |
| MAPK Signaling Up-regulates the activity of hypoxia-inducible factors by its effects on p300 Sang, N., Stiehl, D.P. Bohensky, J., Leshchinsky, I., Srinivas, V., and Caro, J. J. Biol. Chem., Apr 2003; 278: 14013 – 14019. |
| Journal: Journal of Cell Science | Apr-03 |
| Intracellular localisation of human HIF-1 hydroxylases: implications for oxygen sensing Eric Metzen, Utta Berchner-Pfannschmidt, Petra Stengel, Jan H. Marxsen, Ineke Stolze, Matthias Klinger, Wei Qi Huang, Christoph Wotzlaw, Thomas Hellwig-Bürgel, Wolfgang Jelkmann, Helmut Acker, and Joachim Fandrey J. Cell Sci., Apr 2003; 116: 1319 - 1326. |
| Journal: The Journal of Clinical Investigation | Apr-03 |
| Expansion of human SCID-repopulating cells under hypoxic conditions Danet, G. H., Y. Pan, J. L. Luongo, D. A. Bonnet, and M. C. Simon J. Clin. Investigation, Apr 2003; 112: 126 - 135. |
| Journal: The Journal of Clinical Investigation | Apr-03 |
| Hypoxia-induced endocytosis of Na,K-ATPase in alveolar epithelial cells is mediated by mitochondrial reactive oxygen species and PKC- Dada, L., N. Chandel, C. Pedemonte, K.M. Ridge, A.M. Bertorello and J.I. Sznajder. J. Clin. Invest., Apr 2003; 111: 1057 – 1064. |
| Journal: Microbiology | Jan-03 |
| Comparison of real-time PCR with SYBR Green I or 5'-nuclease assays and dot-blot hybridization with rDNA-targeted oligonucleotide probes in quantification of selected faecal bacteria Erja Malinen, Anna Kassinen, Teemu Rinttilä, and Airi Palva Microbiology, Jan 2003; 149: 269 - 277. |
| Journal: The Journal of Neuroscience | Dec-02 |
| Erythropoietin Is a Paracrine Mediator of Ischemic Tolerance in the Brain: Evidence from an In Vitro Model Karsten Ruscher, Dorette Freyer, Maria Karsch, Nikolai Isaev, Dirk Megow, Birgit Sawitzki, Josef Priller, Ulrich Dirnagl, and Andreas Meisel J. Neurosci., Dec 2002; 22: 10291 - 10301. |
| Journal: The Journal of Bacteriology | Dec-02 |
| Isolation of Three New Surface Layer Protein Genes (slp) from Lactobacillus brevis ATCC 14869 and Characterization of the Change in Their Expression under Aerated and Anaerobic Conditions Miia Jakava-Viljanen, Silja Åvall-Jääskeläinen, Paul Messner, Uwe B. Sleytr, and Airi Palva J. Bacteriol., Dec 2002; 184: 6786 - 6795. |
| Journal: Journal of Biological Chemistry | Dec-02 |
| Induction of Hypoxia-inducible Factor-1 by Transcriptional and Translational Mechanisms Elisabeth L. Pagé, Geneviève A. Robitaille, Jacques Pouysségur, and Darren E. Richard J. Biol. Chem., Dec 2002; 277: 48403 - 48409. |
| Journal: American Journal of Physiology - Lung Cellular and Molecular Physiology | Nov-02 |
| Hypoxic but not anoxic stabilization of HIF-1 requires mitochondrial reactive oxygen species Clara Schroedl, David S. McClintock, G. R. Scott Budinger, and Navdeep S. Chandel Am J Physiol Lung Cell Mol Physiol, Nov 2002; 283: 922 - 931. |
| Journal: Molecular and Cellular Biology | Oct-02 |
| Regulation of Hypoxia-Inducible Factor 1 Expression and Function by the Mammalian Target of Rapamycin Christine C. Hudson, Mei Liu, Gary G. Chiang, Diane M. Otterness, Dawn C. Loomis, Fiona Kaper, Amato J. Giaccia, and Robert T. Abraham Mol. Cell. Biol., Oct 2002; 22: 7004 - 7014. |
| Journal: Stroke | Jul-02 |
| Tolerance Against Ischemic Neuronal Injury Can Be Induced by Volatile Anesthetics and Is Inducible NO Synthase Dependent Krisztian J. Kapinya, Diana Löwl, Carsten Fütterer, Martin Maurer, Klaus F. Waschke, Nikolaj K. Isaev, and Ulrich Dirnagl Stroke, Jul 2002; 33: 1889 - 1898. |
| Journal: Journal of Biological Chemistry | Jun-02 |
| Calcium/Calmodulin-dependent Protein Kinase II2 and Isoforms Regulate Potassium Currents of Rat Brain Capillary Endothelial Cells under Hypoxic Conditions Zsolt Balla, Brigitte Hoch, Peter Karczewski, and Ingolf E. Blasig J. Biol. Chem., Jun 2002; 277: 21306 - 21314. |
| Journal: Journal of Biological Chemistry | May-02 |
| Hypoxia Sensitizes Cells to Nitric Oxide-induced Apoptosis Vivian Y. Lee, David S. McClintock, Matthew T. Santore, G. R. Scott Budinger, and Navdeep S. Chandel J. Biol. Chem., May 2002; 277: 16067 - 16074. |
| Journal: American Journal of Physiology - Lung Cellular and Molecular Physiology | Apr-02 |
| Anoxia-induced apoptosis occurs through a mitochondria-dependent pathway in lung epithelial cells Matthew T. Santore, David S. McClintock, Vivian Y. Lee, G. R. Scott Budinger, and Navdeep S. Chandel Am J Physiol Lung Cell Mol Physiol, Apr 2002; 282: 727. |
| Journal: Journal of Biological Chemistry | Apr-02 |
| Phosphatidylinositol 3-Kinase/Akt Signaling Is Neither Required for Hypoxic Stabilization of HIF-1 nor Sufficient for HIF-1-dependent Target Gene Transcription Andrew M. Arsham, David R. Plas, Craig B. Thompson, and M. Celeste Simon J. Biol. Chem., Apr 2002; 277: 15162 - 15170. |
| Journal: Journal of Biological Chemistry | Feb-02 |
| Hypoxia-inducible factor-1 (HIF-1) mediated expression of the 6-phosphofructo-2-kinase/fructose-2-6-bisphosphatase (PFKBF3) gene: its possible role in the Warburg effect Minchenko, A., Leshchinsky, I., Opentanova, I., Sang, N., Srinivas, V., Armstead V., and Caro, J. J. Biol. Chem., Feb 2002; 277: 6183 - 6187 |
| Journal: The Veterinary Record | Feb-02 |
| First confirmation of porcine colonic spirochaetosis caused by Brachyspira pilosicoli in Iberian pigs in Spain M. L. de Arriba, A. B. Vidal, J. Pozo,, A. Martínez, P. Rubio, A. Carvajal, and G. E. Duhamel Vet Rec., Feb 2002; 150: 250 - 251. |
| Journal: Molecular Endocrinology | Feb-02 |
| Isoform-Specific Expression of Hypoxia-Inducible Factor-1 During the Late Stages of Mouse Spermiogenesis Hugo H. Marti, Dörthe M. Katschinski, Klaus F. Wagner, Leonhard Schäffer, Bettina Stier, and Roland H. Wenger Mol. Endocrinol., Feb 2002; 16: 234 - 243. |
| Journal: Molecular and Cellular Biology | Jan-02 |
| Bcl-2 Family Members and Functional Electron Transport Chain Regulate Oxygen Deprivation-Induced Cell Death David S. McClintock, Matthew T. Santore, Vivian Y. Lee, Joslyn Brunelle, G. R. Scott Budinger, Wei-Xing Zong, Craig B. Thompson, Nissim Hay, and Navdeep S. Chandel Mol. Cell. Biol., Jan 2002; 22: 94 - 104. |
| Journal: Journal of Cell Science | Oct-01 |
| The nucleus, a site for signal termination by sequestration and inactivation of p42/p44 MAP kinases Véronique Volmat, Montserrat Camps, Steve Arkinstall, Jacques Pouysségur, and Philippe Lenormand J. Cell Sci., Oct 2001; 114: 3433 - 3443. |
| Journal: Cell | Oct-01 |
| C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation Andrew C.R. Epstein, Jonathan M. Gleadle, Luke A. McNeill, Kirsty S. Hewitson, John O'Rourke, David R. Mole, Mridul Mukherji, Eric Metzen, Michael I. Wilson, Anu Dhanda, Ya-Min Tian, Norma Masson, Donald L. Hamilton, Panu Jaakkola, Robert Barstead, Jonathan Hodgkin, Patrick H. Maxwell, Christopher W. Pugh, Christopher J. Schofield, and Peter J. Ratcliffe Cell, Oct 2001; 107: 43 – 54. |
| Journal: EMBO Report | Jul-01 |
| Hypoxia-inducible factor-1 (HIF-1) escapes O2-driven proteasomal degradation irrespective of its subcellular localization: nucleus or cytoplasm Edurne Berra, Danièle Roux, Darren E. Richard, and Jacques Pouysségur EMBO Rep., Jul 2001; 2: 615 - 620. |
| Journal: Blood | Jul-01 |
| Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain Emma C. Vaux, Eric Metzen, Kay M. Yeates, and Peter J. Ratcliffe Blood, Jul 2001; 98: 296 - 302. |
| Journal: Science | Apr-01 |
| Targeting of HIF- to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation Panu Jaakkola, David R. Mole, Ya-Min Tian, Michael I. Wilson, Janine Gielbert, Simon J. Gaskell, Alexander von Kriegsheim, Holger F. Hebestreit, Mridul Mukherji, Christopher J. Schofield, Patrick H. Maxwell, Christopher W. Pugh, and Peter J. Ratcliffe Science, Apr 2001; 292: 468 - 472. |
| Journal: Journal of Biological Chemistry | Aug-00 |
| Nonhypoxic Pathway Mediates the Induction of Hypoxia-inducible Factor 1 in Vascular Smooth Muscle Cells Darren E. Richard, Edurne Berra, and Jacques Pouysségur J. Biol. Chem., Aug 2000; 275: 26765 - 26771. |
| Journal: Journal of Biological Chemistry | Mar-00 |
| Identification of Alternative Spliced Variants of Human Hypoxia-inducible Factor-1 Emmanuel Gothié, Darren E. Richard, Edurne Berra, Gilles Pagès, and Jacques Pouysségur J. Biol. Chem., Mar 2000; 275: 6922 - 6927. |
| Journal: Biochemical and Biophysical Research Communications | Dec-99 |
| Angiogenesis: How a Tumor Adapts to Hypoxia Darren E. Richard, Edurne Berra, and Jacques Pouysségur Biochemical and Biophysical Research Communications, Dec 1999; 266: 718-722. |
| Journal: Journal of Biological Chemistry | Nov-99 |
| p42/p44 Mitogen-activated Protein Kinases Phosphorylate Hypoxia-inducible Factor 1 (HIF-1) and Enhance the Transcriptional Activity of HIF-1 Darren E. Richard, Edurne Berra, Emmanuel Gothié, Danièle Roux, and Jacques Pouysségur J. Biol. Chem., Nov 1999; 274: 32631-32637. |
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